99458-24-9

Upstream product

• 99528-65-1 (2R,3R)-(+)-methyl 3-phenyloxiranecarboxylate 
• 99458-18-1 (2R,3S)-N-benzoyl-O-<(benzyloxy)methyl>-3-phenylisoserine methyl ester 
• 99528-63-9 (2S,3R)-2,3-epoxy-3-phenylpropan-1-ol 
• 32981-85-4 methyl (2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropanoate 
• 99458-15-8 Methyl (2R,3S)-(+)-2-hydroxy-3-azido-3-phenyl-propionate 
• 99458-21-6 (2R,3S)-N-benzoyl-O-<(benzyloxy)methyl>-3-phenylisoserine 
• 4064-06-6 1,2:3,4-di-O-isopropylidene-α-D-galactopyranose 
• 99458-16-9 (2R,3S)-(+)-methyl 3-azido-2-benzoly-3-phenylpropionate 

Downstream Products

• 99458-26-1 (2R,3S)-3-Benzoylamino-2-hydroxy-3-phenyl-propionic acid (3aR,5R,5aS,8aS,8bR)-2,2,7,7-tetramethyl-tetrahydro-bis[1,3]dioxolo[4,5-b;4',5'-d]pyran-5-ylmethyl ester 

Relevant academic research and scientific papers

An Efficient, Enantioselective Synthesis of the Taxol Side Chain

An asymmetric epoxidation (70-80percent ee) and a highly regioselective epoxide cleavage have been used as the key reactions in the synthesis of the taxol side chain methyl ester (2; 95percent ee, 23percent overall yield from phenylacetylene.Transesterifications of 2 (in four steps) have been effected and are exemplified with (-)-isopinocampheol (8), 1,2;3,4-di-O-isopropylidene-D-galactopyranose (9), and methyl gibberellate (10).