99500-35-3Relevant academic research and scientific papers
Regio- and chemoselective C-H chlorination/bromination of electron-deficient arenes by weak coordination and study of relative directing-group abilities
Sun, Xiuyun,Shan, Gang,Sun, Yonghui,Rao, Yu
supporting information, p. 4440 - 4444 (2013/05/22)
It's all relative: A practical and efficient PdII-catalyzed regio- and chemoselective chlorination/bromination has been developed for the facile synthesis of a broad range of aromatic chlorides. The reaction demonstrates excellent reactivity, good functional-group tolerance, and high yields. A preliminary study was conducted to evaluate relative directing-group abilities of various functionalities. Copyright
FUSED HETEROCYCLIC RING DERIVATIVE AND USE THEREOF
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Page/Page column 94, (2012/07/14)
The present invention provides a fused heterocycle derivative having a strong Smo inhibitory activity, and use thereof. Specially, the present invention relates to a compound represented by the formula wherein each symbol is as defined in the specification, or salt thereof, and a medicament containing the compound or a prodrug thereof, which is an Smo inhibitor or an agent for the prophylaxis or treatment of cancer.
Insertion of arynes into carbon-halogen σ-bonds: Regioselective acylation of aromatic rings
Yoshida, Hiroto,Mimura, Yasuhiro,Ohshita, Joji,Kunai, Atsutaka
, p. 2405 - 2407 (2008/02/08)
Arynes were found to insert into carbon-halogen σ-bonds of various acid halides, enabling acyl and halogen moieties to be introduced simultaneously into adjacent positions of aromatic rings. The Royal Society of Chemistry.
Substituted alkylidene imidazoles
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, (2008/06/13)
This disclosure relates to a class of novel substituted alkylidene imidazole derivatives and pharmaceutically acceptable salts thereof. The disclosure further describes pharmaceutical compositions containing such compounds and to the use of such compounds
