99520-05-5

Usage

Uses

Used in Pharmaceutical Industry:
2,6-Dichloro-4-Methylbenzoic acid is used as a building block for the synthesis of various pharmaceuticals. Its strong acidic properties and reactivity make it a valuable component in the development of new drugs and medications.
Used in Agrochemical Industry:
In the agrochemical industry, 2,6-Dichloro-4-Methylbenzoic acid is used as a building block for the synthesis of agrochemicals. Its properties contribute to the creation of effective compounds for agricultural applications, such as pesticides and herbicides.
Used in Dye and Pigment Production:
2,6-Dichloro-4-Methylbenzoic acid is used as an intermediate in the production of dyes and pigments. Its chemical structure allows for the creation of a wide range of colors and hues, making it an essential component in the formulation of various dyes and pigments.
Used in Organic Synthesis:
2,6-Dichloro-4-Methylbenzoic acid is used as a catalyst in organic synthesis reactions. Its strong acidic properties facilitate various chemical transformations, making it a valuable tool in the synthesis of complex organic compounds.
Used in Research and Development:
2,6-Dichloro-4-Methylbenzoic acid is widely used in the study and development of new compounds for various industries. Its versatility and reactivity make it an essential component in the exploration of novel chemical entities and their potential applications.

Upstream product

• 124-38-9 carbon dioxide 
• 25186-47-4 3,5-dichlorotoluene 
• 94-08-6 4-methylbenzoic acid ethyl ester 
• 99500-35-3 ethyl 2-chloro-4-methylbenzoate 

Downstream Products

• 99508-23-3 2',6',4''-trichloro-4'-methylbenzophenone 
• 25186-47-4 3,5-dichlorotoluene 
• 1098620-10-0 methyl 2,6-dichloro-4-aldehyde benzoate 
• 135340-70-4 5-Amino-1-[3,5-dichloro-4-(4-trichlorovinyl-benzoyl)-benzyl]-1H-[1,2,3]triazole-4-carboxylic acid amide 
• 135340-72-6 4-[4-(5-Amino-4-carbamoyl-[1,2,3]triazol-1-ylmethyl)-2,6-dichloro-benzoyl]-benzoic acid methyl ester 
• 135340-71-5 5-Amino-1-[3,5-dichloro-4-(4-cyano-benzoyl)-benzyl]-1H-[1,2,3]triazole-4-carboxylic acid amide 
• 135340-73-7 5-amino-1-[4-(3,4-dichlorobenzoyl)-3,5-dichlorobenzyl]-1,2,3-triazole-4-carboxamide 
• 135340-77-1 5-Amino-3-[3,5-dichloro-4-(4-chloro-benzoyl)-benzyl]-3H-[1,2,3]triazole-4-carboxylic acid amide 
• 99880-60-1 5-Amino-1-(4-benzoyl-3,5-dichlorobenzyl)-1,2,3-triazole-4-carboxamide 
• 135340-64-6 (4-Azidomethyl-2,6-dichloro-phenyl)-(3,4-dichloro-phenyl)-methanone 
• 135340-54-4 (4-Bromomethyl-2,6-dichloro-phenyl)-(4-trichlorovinyl-phenyl)-methanone 
• 135340-63-5 4-(4-Azidomethyl-2,6-dichloro-benzoyl)-benzonitrile 
• 135340-56-6 4-(4-Bromomethyl-2,6-dichloro-benzoyl)-benzoic acid methyl ester 
• 135340-42-0 (2,6-Dichloro-4-methyl-phenyl)-(4-trichlorovinyl-phenyl)-methanone 

Relevant academic research and scientific papers

PYRAZOLE AMIDE DERIVATIVE

The present invention relates to a novel compound having a function of inhibiting RORγ activity. The present invention also relates to pharmaceutical composition comprising the compound, a use of the compound in treating or preventing autoimmune diseases, inflammatory diseases, metabolic diseases, or cancer diseases.

Regio- and chemoselective C-H chlorination/bromination of electron-deficient arenes by weak coordination and study of relative directing-group abilities

It's all relative: A practical and efficient PdII-catalyzed regio- and chemoselective chlorination/bromination has been developed for the facile synthesis of a broad range of aromatic chlorides. The reaction demonstrates excellent reactivity, good functional-group tolerance, and high yields. A preliminary study was conducted to evaluate relative directing-group abilities of various functionalities. Copyright

Benzylated 1,2,3-triazoles as anticoccidiostats

Substituted 5-amino-4-carbamoyl-1,2,3-triazoles 3a-w were prepared by two synthetic schemes and evaluated in vivo for anticoccidial activity. Both schemes proceeded by brominating appropriately substituted toluenes 4a-s,v to 5a-s,v. In Scheme I, the brominated benzyl analogues 5 were converted to the corresponding benzyl azides 6, which were treated with cyanoacetamide to yield 1-substituted-5-amino-4-carbamoyl-1,2,3-triazoles 3. In Scheme II, the benzyl halides 5 were employed to alkylate the sodium salt of 5-amino-4-carbamoyl-1,2,3-triazole (7). Preliminary screening data against Eimeria acervulina and E. tenella in chickens suggested structural requirements for maximizing activity. Further evaluation against a relatively resistant series of eight Eimeria field isolates revealed L-651,582 (3a) to be a highly effective coccidiostat. However, unacceptable tissue residues precluded further development. Mechanistic studies on this series of 5-amino-4-carbamoyl-1,2,3-triazoles and, in particular, on L-651,582 (3a) revealed that its mode of action does not involve inhibition of IMP dehydrogenase, but probably interferes with host cell calcium entry. In addition, L-651,582 has been found to have antiproliferative activity in several disease models and was recently reported to possess antimetastatic activity in a model of ovarian cancer progression.

5-amino or substituted amino 1,2,3-triazoles

Novel 5-amino or substituted amino 1,2,3-triazoles are disclosed as having anticoccidial activity. The compounds are useful for controlling coccidiosis when administered in minor quantities to animals, in particular to poultry, usually in admixture with a