99513-17-4

Usage

Uses

Used in Organic Synthesis:
5-bromo-1,2-dimethyl-1H-benzo[d]imidazole is used as a building block for the synthesis of various bioactive molecules and pharmaceuticals. Its unique structure allows for the creation of a wide range of compounds with potential applications in various industries.
Used in Pharmaceutical Research:
5-bromo-1,2-dimethyl-1H-benzo[d]imidazole is used as a starting material for the development of new drugs. Its potential therapeutic properties are being studied for the treatment of various medical conditions, making it a valuable asset in pharmaceutical research.
Used in Industrial Applications:
5-bromo-1,2-dimethyl-1H-benzo[d]imidazole may also find use in other industrial applications due to its unique chemical properties. Its versatility allows for its use in a variety of settings, from the development of new materials to the improvement of existing ones.
Used as a Reagent in Chemical Reactions:
5-bromo-1,2-dimethyl-1H-benzo[d]imidazole can be used as a reagent in various chemical reactions, facilitating the synthesis of desired products. Its presence can help to drive reactions forward, making it a useful tool in the laboratory and in industrial processes.

Upstream product

• 2876-08-6 1,2-dimethyl-1H-benzimidazole 
• 108-24-7 acetic anhydride 
• 53484-26-7 N-methyl-4-bromo-2-nitroaniline 
• 75-36-5 acetyl chloride 
• 69038-76-2 2-N-methylamino-5-bromoaniline 
• 364-73-8 4-Bromo-1-fluoro-2-nitrobenzene 
• 1445-45-0 Trimethyl orthoacetate 

Downstream Products

• 227306-27-6 1,2-dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazole 
• 3527-19-3 1,2-dimethyl-1H-benzo[d]imidazole-5-amine 
• 51073-43-9 3-amino-1,2-dimethyl-1H-benzo[d]imidazole-3-ium 2,4,6-trimethylbenzenesulfonate 
• 1206791-27-6 3-{(S)-1-[4-(1,2-dimethyl-1H-benzo[d]imidazol-5-yl)phenyl]ethyl}-6-(2-hydroxy-2-methylpropyl)-6-isopropyl-1,3-oxazinan-2-one 

Relevant academic research and scientific papers

INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES

Provided herein are heteroaryl inhibitors of fibroblast growth factor receptor kinases, pharmaceutical compositions comprising said compounds, and methods for using said compounds for the treatment of diseases.

SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE

The present invention provides novel heteroaryl compounds, pharmaceutical acceptable salts and formulations thereof. They are useful in preventing, managing, treating or lessening the severity of a protein kinase-mediated disease. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of protein kinase-mediated disease.

Substituted heteroaryl compounds and compositions and uses thereof (by machine translation)

The invention discloses substituted heteroaryl compounds and compositions thereof and their use. The compounds of formula (I) compound or type shown in (I) a compound represented by stereo isomers, tautomers, nitrogen oxide, solvate, metabolite, pharmaceutically acceptable salt or its prodrug. The invention also provides a pharmaceutical composition, the compounds and pharmaceutical compositions can be regulated protein kinase, particularly Aurora kinase and JAK kinase activity, for the prevention, treatment, treatment and reduce protein kinase, in particular JAK kinase activity mediated diseases or disorders. (by machine translation)

BROMINATION OF 1,2-DIMETHYLBENZIMIDAZOLE WITH N-BROMOSUCCINIMIDE

The reaction of 1,2-dimethylbenzimidazole with N-bromosuccinimide was studied under conditions of free-radical substitution.The influence of the reactant ratio and the mode of introduction of the brominating agent on the course of the reaction was investigated.It was found that bromination of 1,2-dimethylbenzimidazole with excess N-bromosuccinimide in the presence of benzoyl peroxide gives polybromoalkyl and polybromoaryl derivatives.