99513-17-4

Basic information

• Product Name: 5-broMo-1,2-diMethyl-1H-benzo[d]iMidazole
• Synonyms: 5-broMo-1,2-diMethyl-1H-benzo[d]iMidazole;5-Bromo-1,2-dimethyl-1,3-benzodiazole
• CAS NO: 99513-17-4
• Molecular Formula: C₉H₉BrN₂
• Molecular Weight: 225.08516
• Mol File: 99513-17-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-broMo-1,2-diMethyl-1H-benzo[d]iMidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-broMo-1,2-diMethyl-1H-benzo[d]iMidazole(99513-17-4)
• EPA Substance Registry System: 5-broMo-1,2-diMethyl-1H-benzo[d]iMidazole(99513-17-4)

Safety Data

• Hazardous Substances Data: 99513-17-4(Hazardous Substances Data)

Usage

General Description

5-bromo-1,2-dimethyl-1H-benzo[d]imidazole is a chemical compound with the molecular formula C9H9BrN2. It belongs to the class of benzo[d]imidazole derivatives and contains a bromine atom and two methyl groups attached to the benzene ring. 5-bromo-1,2-dimethyl-1H-benzo[d]imidazole has applications in organic synthesis and pharmaceutical research, as it can be used as a building block for the synthesis of various bioactive molecules and pharmaceuticals. It has been studied for its potential therapeutic properties in the treatment of various medical conditions. Additionally, 5-bromo-1,2-dimethyl-1H-benzo[d]imidazole may also find use in other industrial applications and as a reagent in chemical reactions.

Upstream product

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• 108-24-7 acetic anhydride 

Downstream Products

• 3527-19-3 1,2-dimethyl-1H-benzo[d]imidazole-5-amine 
• 51073-43-9 3-amino-1,2-dimethyl-1H-benzo[d]imidazole-3-ium 2,4,6-trimethylbenzenesulfonate 
• 227306-27-6 1,2-dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazole 
• 1206791-27-6 3-{(S)-1-[4-(1,2-dimethyl-1H-benzo[d]imidazol-5-yl)phenyl]ethyl}-6-(2-hydroxy-2-methylpropyl)-6-isopropyl-1,3-oxazinan-2-one 

Relevant articles and documents

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SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE

The present invention provides novel heteroaryl compounds, pharmaceutical acceptable salts and formulations thereof. They are useful in preventing, managing, treating or lessening the severity of a protein kinase-mediated disease. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of protein kinase-mediated disease.

BROMINATION OF 1,2-DIMETHYLBENZIMIDAZOLE WITH N-BROMOSUCCINIMIDE

The reaction of 1,2-dimethylbenzimidazole with N-bromosuccinimide was studied under conditions of free-radical substitution.The influence of the reactant ratio and the mode of introduction of the brominating agent on the course of the reaction was investigated.It was found that bromination of 1,2-dimethylbenzimidazole with excess N-bromosuccinimide in the presence of benzoyl peroxide gives polybromoalkyl and polybromoaryl derivatives.