99529-52-9

Upstream product

• 85785-76-8 (+/-)-(2'E,4'E)-3-<5'-(3,3-ethylenedioxy-1,2,6-trimethylcyclohexyl)-3'-methyl-2',4'-pentadienyl>-1,5-dichloro-6-methyl-2,4-cyclohexanedione 
• 6153-06-6 3-methylpent-2-en-4-yn-1-ol 
• 85785-71-3 (+/-)-(2EZ,4E)-5-(1',2',6'-trimethyl-3'-oxocyclohexyl)-3-methyl-2,4-pentadien-1-ol 
• 85785-75-7 (+/-)-(2E,4E)-5-(3',3'-ethylenedioxy-1',2',6'-trimethylcyclohexyl)-3-methyl-2,4-pentadienyl bromide 
• 85785-72-4 (+/-)-(2EZ,4E)-5-(1',2',6'-trimethyl-3'-oxocyclohexyl)-3-methyl-2,4-pentadienyl acetate 
• 85785-73-5 (+/-)-(2EZ,4E)-5-(3',3'-ethylenedioxy-1',2',6'-trimethylcyclohexyl)-3-methyl-2,4-pentadienyl acetate 
• 85912-78-3 (+/-)-(2'E,4'E)-3-<5'-(3,3-ethylenedioxy-1,2,6-trimethylcyclohexyl)-3'-methyl-2',4'-pentadienyl>-2,4-dimethoxy-6-methyl-1,4-cyclohexadiene 
• 85785-74-6 (+/-)-(2E,4E)-5-(3',3'-ethylenedioxy-1',2',6'-trimethylcyclohexyl)-3-methyl-2,4-pentadien-1-ol 
• 41967-81-1 (E)-tetrahydro-2-<(3-methyl-2-penten-4-ynyl)oxy>-2H-pyran 
• 10463-42-0 3,4-dimethyl-cyclohex-2-enone 
• 307492-54-2 (-)-benzyl (4E,6E)-7-[(1R,2R,6R)-3,3-ethylenedioxy-1,2,6-trimethylcyclohexyl]-5-methylhepta-4,6-dien-1-ynyl ether 
• 89162-97-0 (R)-(+)-3,4-dimethyl-2-cyclohexen-1-one 
• 85785-72-4 (2EZ,4E,1'R,2'R,6'R)-(-)-5-(1',2',6'-trimethyl-3'-oxocyclohexyl)-3-methyl-2,4-pentadienyl acetate 
• 85785-74-6 (+/-)-(2EZ,4E)-5-(3',3'-ethylenedioxy-1',2',6'-trimethylcyclohexyl)-3-methyl-2,4-pentadien-1-ol 

Downstream Products

• 26166-39-2 3-Chloro-4,6-dihydroxy-2-methyl-5-[(2Z,4E)-3-methyl-5-((1S,2S,6S)-1,2,6-trimethyl-3-oxo-cyclohexyl)-penta-2,4-dienyl]-benzaldehyde 
• 26166-39-2 (+/-) ascochlorin 
• 91854-87-4 3-Chloro-4,6-dihydroxy-2-methyl-5-[(2Z,4E)-3-methyl-5-((6R,7R,8R)-6,7,8-trimethyl-1,4-dioxa-spiro[4.5]dec-7-yl)-penta-2,4-dienyl]-benzaldehyde 
• 99529-53-0 3-Chloro-4,6-dihydroxy-2-methyl-5-[(2E,4E)-3-methyl-5-((6R,7R,8R)-6,7,8-trimethyl-1,4-dioxa-spiro[4.5]dec-7-yl)-penta-2,4-dienyl]-benzaldehyde 
• 91854-87-4 3-chloro-4,6-dihydroxy-2-methyl-5-decane)-2,4-pentadienyl>benzaldehyde 

Relevant academic research and scientific papers

Total synthesis of (-)-ascochlorin via a cyclobutenone-based benzannulation strategy.

The application of a convergent benzannulation strategy in an efficient synthesis of (-)-ascochlorin is described.

SYNTHESIS OF THE NATURAL ENANTIOMERS OF ASCOCHLORIN, ASCOFURANONE AND ASCOFURANOL

Three fungal metabolites with a common structural feature as prenylated phenols were synthesized in their naturally occuring and optically active forms: ascochlorin benzaldehyde>, ascofuranone and ascofuranol benzaldehyde>. (+)-Ascofuranone and (+)-ascofuranol were also synthesized.By the present synthesis the absolute configuration of the natural (-)-ascofuranol was established as (1''S,4''S).

SYNTHESIS OF (+/-)-ASCOCHLORIN, (+/-)-ASCOFURANONE AND LL-Z1272α

Three antibiotics with a common structural feature as prenylated phenols were synthesized: (+/-)-ascochlorin (5-chloro-2,4-dihydroxy-6-methyl-3-benzaldehyde), (+/-)-ascofurano