99584-85-7

Basic information

• Product Name: 3-METHYL-4-NITROBENZAMIDE
• Synonyms: 3-METHYL-4-NITROBENZAMIDE;3-METHYL-4-NITROBENZAMIDE, 97%%;4-Nitro-m-toluamide
• CAS NO: 99584-85-7
• Molecular Formula: C₈H₈N₂O₃
• Molecular Weight: 180.16
• EINECS: -0
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 99584-85-7.mol
• Article Data: 5

Chemical Properties

• Melting Point: 158-160°C
• Boiling Point: 321℃
• Flash Point: 148℃
• Appearance: /
• Density: 1.322
• Vapor Pressure: 0.000316mmHg at 25°C
• Refractive Index: 1.599
• Storage Temp.: 2-8°C
• PKA: 15.14±0.50(Predicted)
• Water Solubility: Soluble in alcohol, slightly soluble in hot water.
• BRN: 2264048
• CAS DataBase Reference: 3-METHYL-4-NITROBENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHYL-4-NITROBENZAMIDE(99584-85-7)
• EPA Substance Registry System: 3-METHYL-4-NITROBENZAMIDE(99584-85-7)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 99584-85-7(Hazardous Substances Data)

Usage

Uses

3-Methyl-4-nitrobenzamide is used as synthetic organic intermediates.

InChI:InChI=1/C8H8N2O3/c1-5-4-6(8(9)11)2-3-7(5)10(12)13/h2-4H,1H3,(H2,9,11)

Upstream product

• 3113-71-1 3-methyl-4-nitrobenzoic acid 
• 96784-54-2 3-methyl-4-nitrobenzonitrile 
• 35675-46-8 3-methyl-4-nitro-benzoyl chloride 

Downstream Products

• 96784-54-2 3-methyl-4-nitrobenzonitrile 
• 106037-36-9 4-amino-3-methylbenzamide 
• 229633-56-1 1-(3-methyl-4-nitrobenzyl)methanamine 
• 104478-90-2 methyl (3-methyl-4-nitrophenyl)carbamate 
• 1208318-94-8 1-amino-(2-methyl-4-(sulfamoylamino)phenyl) 

Relevant articles and documents

Novel commercial scale synthetic approach for 5-cyanoindole: A potential intermediate for vilazodone hydrochloride, an antidepressant drug

Present work describes the synthesis of 5-cyanoindole, a common intermediate used in various synthetic route of the antidepressant vilazodone hydrochloride. The protocol is both robust and commercially viable, utilizing readily available and low-cost materials and the isomers are environmental friendly than previously reported routes through its evading use of cyanide reagents and heavy metals.

DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS

The present invention relates to compounds of formula (I) wherein Q is (Q1) or (Q2) G1 is oxygen or sulfur; Y1 is oxygen, sulfur or CH2; Y2, Y3 and Y4 are each independently C-H, C-R5 or nitrogen, wherein no more than one of Y2, Y3 and Y4 is C-R5; Y5 is hydrogen, halogen, C1-C8alkyl, C1-C8haloalkyl or C3-C8cycloalkyl; Y6 is hydrogen, halogen, cyano, C1-C8alkyl, C1-C8haloalkyl or C3-C8cycloalkyl; R1a is hydrogen, C1-C8alkyl, C1-C8alkoxy, C1-C8alkylcarbonyl or C1-C8alkoxycarbonyl; R1b is hydrogen, C1-C8alkyl, C1-C8alkylcarbonyl or C1-C8alkoxycarbonyl; R3 is C1-C8haloalkyl; R4 is aryl or aryl substituted by one to five R10, or heteroaryl or heteroaryl substituted by one to five R10; R6a is hydrogen, cyano, C1-C8alkyl, C1-C8haloalkyl or C3-C8cycloalkyl; R6b is hydrogen, cyano, C1-C8alkyl, C1-C8haloalkyl or C3-C8cycloalkyl; or R6a and R6b together with the carbon atom to which they are attached may form a 3 to 6-membered carbocyclic ring; and R2a, R2b, R and R are as defined in the claims. The invention also relates to methods of controlling insects, acarines, nematodes or molluscs which comprises applying to a pest, to a locus of a pest, or to a plant susceptible to attack by a pest an insecticidally, acaricidally, nematicidally or molluscicidally effective amount of a compound of formula I.

Anthelmintically active benzenepropanamide derivatives

This invention is directed to a method for treating helminthiasis in an animal which method comprises administering to an animal in need thereof an anthelmintically effective amount of a compound of the Formula (I): STR1 wherein Z is oxygen or sulfur;R 1 is hydrogen or lower alkyl; andR 2, R 3, R 4 and R 5 are independently hydrogen, halo, lower haloalkyl, lower alkoxy, lower haloalkoxy, nitro, cyano, halophenoxy, haloalkylphenoxy, thiocyano or isothiocyano, provided that R 2 and R 3 cannot simultaneously be hydrogen and that R 4 and R 5 cannot simultaneously be hydrogen; or a pharmaceutically acceptable salt thereof, and pharmaceutical compositions formulated therewith. This invention is also directed to novel anthelmintically active benzenepropanamides of Formula (I) wherein Z is oxygen.