99585-98-5

Basic information

• Product Name: 3-CHLORO-N-(3-CHLOROPHENYL)PROPANAMIDE
• Synonyms: 3-chloro-N-(3-chlorophenyl)propanamide(SALTDATA: FREE);3-chloro-N-(3-chlorophenyl)propionamide;Propanamide, N-(3-chlorophenyl)-3-chloro-;3-CHLORO-N-(3-CHLOROPHENYL)PROPANAMIDE
• CAS NO: 99585-98-5
• Molecular Formula: C₉H₉Cl₂NO
• Molecular Weight: 218.08
• Mol File: 99585-98-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 384.5 °C at 760 mmHg
• Flash Point: 186.3 °C
• Appearance: /
• Density: 1.343 g/cm³
• Vapor Pressure: 4.08E-06mmHg at 25°C
• Refractive Index: 1.591
• CAS DataBase Reference: 3-CHLORO-N-(3-CHLOROPHENYL)PROPANAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CHLORO-N-(3-CHLOROPHENYL)PROPANAMIDE(99585-98-5)
• EPA Substance Registry System: 3-CHLORO-N-(3-CHLOROPHENYL)PROPANAMIDE(99585-98-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 99585-98-5(Hazardous Substances Data)

Usage

General Description

3-chloro-N-(3-chlorophenyl)propanamide is a chemical compound with the molecular formula C9H10Cl2NO. It is a white to off-white crystalline powder with a molecular weight of 224.087 g/mol. 3-chloro-N-(3-chlorophenyl)propanamide is an amide derivative with a chlorophenyl group attached to the nitrogen atom. It is primarily used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 3-chloro-N-(3-chlorophenyl)propanamide may undergo reactions such as hydrolysis, oxidation, and reduction when exposed to certain conditions. Additionally, it is important to handle this compound with proper safety precautions as it may pose hazards if mishandled.

InChI:InChI=1/C9H9Cl2NO/c10-5-4-9(13)12-8-3-1-2-7(11)6-8/h1-3,6H,4-5H2,(H,12,13)

Upstream product

• 108-42-9 3-chloro-aniline 
• 625-36-5 2-chloropropionyl chloride 

Downstream Products

• 109507-07-5 N,N-diethyl-β-alanine-(3-chloro-anilide); hydrochloride 
• 137776-95-5 2,7-Dichloro-3-chloromethylquinoline 
• 428832-32-0 3-(3,4-dihydroisoquinolin-2(1H)-yl)-N-(3-chlorophenyl)propanamide 
• 1233488-28-2 C₁₁H₁₁ClN₄OS 

Relevant articles and documents

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Protein arginine methyltransferase 5 (PRMT5) is an epigenetics related enzyme that has been validated as a promising therapeutic target for human cancer. Up to now, two small molecule PRMT5 inhibitors has been put into phase I clinical trial. In the prese

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3-Mercapto-(4H)-1,2,4-triazole has been synthesized from 1-formylthiosemicarbazide. Different N-substituted β-chloropropionamides have been prepared by reacting substituted amines with β- chloropropionylchloride. Different Nsubstituted β-chloropropionamides have been condensed with 3-mercapto-(4H)-1,2,4-triazole in basic medium to obtain various 3-(N-substituted carboxamidoethylthio)-(4H)-1,2,4-triazoles. The structure of the synthesized compounds are confirmed by IR, 1H NMR spectra and elemental analysis. All the compounds have been screened for their analgesic, anti-inflammatory and anxiolytic activity.

5-HT(1A), and D-2 receptor affinity of o-methoxyphenylpiperazine derivatives with terminal benzamide fragment on N-4 alkyl chain. 2

The synthesis of some o-methoxyphenylpiperazines with a benzamide moiety on N-4 alkyl chain was accomplished and their affinity for dopamine and serotonin receptor subtypes was assayed by in vitro receptor binding. The results show that several derivative