99615-68-6

Usage

Uses

Used in Pharmaceutical Industry:
6-Benzothiazolecarboxylic acid, 2,3-dihydro-2-oxo(9CI) is used as a key intermediate in the synthesis of various pharmaceuticals due to its unique chemical properties and potential biological activity. It contributes to the development of new drugs with anti-cancer and anti-inflammatory properties, offering promising therapeutic benefits.
Used in Agrochemical Industry:
In the agrochemical industry, 6-Benzothiazolecarboxylic acid, 2,3-dihydro-2-oxo(9CI) serves as a building block for the synthesis of various agrochemicals, including pesticides and herbicides. Its incorporation into these products enhances their effectiveness in protecting crops and managing pests, contributing to increased agricultural productivity.
Used as a Fluorescent Indicator:
6-Benzothiazolecarboxylic acid, 2,3-dihydro-2-oxo(9CI) is utilized as a fluorescent indicator in various analytical and diagnostic applications. Its fluorescent properties allow for the detection and quantification of specific molecules or ions, aiding in research and quality control processes.
Used as a Cross-linking Agent in Polymer Production:
In the field of material science, 6-Benzothiazolecarboxylic acid, 2,3-dihydro-2-oxo(9CI) is employed as a cross-linking agent in the production of polymers. Its ability to form covalent bonds between polymer chains enhances the mechanical properties and stability of the resulting materials, making them suitable for various applications, such as coatings, adhesives, and plastics.

Upstream product

• 99615-55-1 6-chloroacetyl-2(3H)-benzothiazolone 
• 934-34-9 2(3H)-Benzothiazolone 
• 14543-45-4 4-amino-3-mercaptobenzoic acid 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 79-22-1 methyl chloroformate 
• 1373399-28-0 C₁₀H₁₀INO₄ 
• 68867-21-0 4-amino-3-thiocyanatobenzonitrile 
• 93-85-6 2-aminobenzothiazole-6-carboxylic acid 
• 873-74-5 4-Aminobenzonitrile 
• 133044-44-7 6-acetyl-3H-1,3-benzothiazol-2-one 

Downstream Products

• 1221408-57-6 N-{4-[4-(2-methoxyphenyl)piperazinyl]butyl}benzothiazolin-2-one-6-carboxamide 
• 207552-72-5 6-Chloromethylbenzothiazolin-2-one 
• 207552-73-6 6-Ethoxycarbonylbenzothiazolin-2-one 

Relevant academic research and scientific papers

Benzo[d]thiazol-2(3H)-ones as new potent selective CB2 agonists with anti-inflammatory properties

The high distribution of CB2 receptors in immune cells suggests their important role in the control of inflammation. Growing evidence offers this receptor as an attractive therapeutic target: selective CB2 agonists are able to modula

Compound with dopamine D3 receptor adjusting activity, and applications thereof

The invention relates to a compound with dopamine D3 receptor adjusting activity, and applications thereof, and more specifically discloses dopamine receptor D3R as a novel target of post-traumatic stress disorder (PTSD) in prevention, treatment/or auxiliary treatment of PTSD, and screening of anti-PTSD medicines, and relates to applications of a compound with dopamine receptor D3R adjusting activity in preparation of medicines used for preventing, treatment and/or auxiliary treatment of PTSD.

CuI-catalyzed one-pot synthesis of benzothiazolones from 2-iodoanilines-derived carbamates and sodium sulfide

A copper-catalyzed procedure was developed for assembling benzothiazolones from ethyl 2-iodophenylcarbamates and sodium sulfide. A number of functional groups, such as methoxy, acyl, amide, carboxylate, trifluoromethyl, fluoro, and chloro, were tolerated under these conditions, providing benzothiazolones in good yields.

NOVEL DOPAMINE D3 RECEPTOR LIGANDS, THE PREPARATION AND USE THEREOF

The invention discloses novel piperazine derivatives represented by formula I having activity for modulating dopamine D3 receptor, their stereoisomers, pharmaceutical salts, solvates, and the pharmaceutical compositions containing such compounds, their preparation and the use of such compounds for preventing or treating the diseases correlated with central nervous system disorder, such as Parkinson's disease, schizophrenia, drug addiction and relapse and the like, as well as the use of such compounds for kidney protection and immune modulation, or as implemental medicine for researching the function of D3R and the diseases correlated with disorder of D3R function.

NOVEL DOPAMINE D3 RECEPTOR LIGANDS AND PREPARATION AND MEDICAL USES OF THE SAME

The present invention relates to a novel piperazine derivative represented by Formula I having an activity for regulating dopamine D3 receptor, stereoisomers thereof, pharmaceutically acceptable salts or solvates, and a pharmaceutical composition comprising the compound, a process for preparing the same, and use thereof in the prevention or treatment of a disease associated with central nervous system dysfunction, such as Parkinson''s disease, schizophrenia, drug addiction and relapse, as well as kidney protection and immunoregulation, or as a tool for researching D3R function or diseases associated with D3R dysfunction.

COMPOUND INHIBITING DIPEPTIDYL PEPTIDASE IV

The invention aims to provide a dipeptidyl peptidase IV inhibitor which is satisfactory in respect of activity, stability and safety and has an excellent action as a pharmaceutical agent. The invention is directed to a compound represented by the following general formula or a pharmaceutically acceptable salt thereof: wherein R1 and R2 each represents hydrogen, an optionally substituted C1-6 alkyl group, or -COOR5 whereupon R5 represents hydrogen or an optionally substituted C1-6 alkyl group, or R1 and R2, together with a carbon atom to which they are bound, represent a 3- to 6-membered cycloalkyl group, R3 represents hydrogen or an optionally substituted C6-10 aryl group, R4 represents a hydrogen or a cyano group, D represents -CONR6-, -CO- or -NR6CO-, R6 represents hydrogen or an optionally substituted C1-6 alkyl group, E represents -(CH2)m- whereupon m is an integer of 1 to 3, -CH2OCH2-, or -SCH2-, n is an integer of 0 to 3, and A represents an optionally substituted bicyclic heterocyclic group or bicyclic hydrocarbon group.