99615-68-6

Basic information

• Product Name: 6-Benzothiazolecarboxylicacid,2,3-dihydro-2-oxo-(9CI)
• Synonyms: 6-Benzothiazolecarboxylicacid,2,3-dihydro-2-oxo-(9CI);6-Benzothiazolecarboxylicacid,2,3-dihydro-2-oxo-;2-Hydroxybenzo[d]thiazole-6-carboxylic acid;2,3-dihydro-2-oxo-6-Benzothiazole carbocylic acid;2-Oxo-2,3-dihydro-1,3-benzothiazole-6-carboxylic acid;2-Oxo-2,3-dihydro-benzothiazole-6-carboxylic acid;2,3-Dihydro-2-oxo-6-benzothiazolecarboxylic acid
• CAS NO: 99615-68-6
• Molecular Formula: C₈H₅NO₃S
• Molecular Weight: 195.197
• EINECS: 1312995-182-4
• Product Categories: BENZOTHIAZOLE
• Mol File: 99615-68-6.mol
• Article Data: 8

Chemical Properties

• Melting Point: >300℃
• Appearance: /
• Density: 1.586±0.06 g/cm3(Predicted)
• PKA: 3.90±0.20(Predicted)
• CAS DataBase Reference: 6-Benzothiazolecarboxylicacid,2,3-dihydro-2-oxo-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Benzothiazolecarboxylicacid,2,3-dihydro-2-oxo-(9CI)(99615-68-6)
• EPA Substance Registry System: 6-Benzothiazolecarboxylicacid,2,3-dihydro-2-oxo-(9CI)(99615-68-6)

Safety Data

• Hazardous Substances Data: 99615-68-6(Hazardous Substances Data)

Usage

General Description

6-Benzothiazolecarboxylic acid, 2,3-dihydro-2-oxo- (9CI) is a heterocyclic organic compound with a molecular formula C9H7NO3S. It is a derivative of benzothiazole and carboxylic acid, and it is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals. The compound has potential biological activity and is being studied for its potential as an anti-cancer and anti-inflammatory agent. It is also used as a fluorescent indicator and as a cross-linking agent in the production of polymers. Overall, 6-Benzothiazolecarboxylic acid, 2,3-dihydro-2-oxo- (9CI) has a wide range of applications in the pharmaceutical, agricultural, and material science industries.

Upstream product

• 14543-45-4 4-amino-3-mercaptobenzoic acid 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 1373399-28-0 C₁₀H₁₀INO₄ 
• 68867-21-0 4-amino-3-thiocyanatobenzonitrile 
• 93-85-6 2-aminobenzothiazole-6-carboxylic acid 
• 873-74-5 4-Aminobenzonitrile 
• 79-22-1 methyl chloroformate 
• 934-34-9 2(3H)-Benzothiazolone 
• 133044-44-7 6-acetyl-3H-1,3-benzothiazol-2-one 
• 99615-55-1 6-chloroacetyl-2(3H)-benzothiazolone 

Downstream Products

• 1221408-57-6 N-{4-[4-(2-methoxyphenyl)piperazinyl]butyl}benzothiazolin-2-one-6-carboxamide 
• 207552-72-5 6-Chloromethylbenzothiazolin-2-one 
• 207552-73-6 6-Ethoxycarbonylbenzothiazolin-2-one 

Relevant articles and documents

Compound with dopamine D3 receptor adjusting activity, and applications thereof

The invention relates to a compound with dopamine D3 receptor adjusting activity, and applications thereof, and more specifically discloses dopamine receptor D3R as a novel target of post-traumatic stress disorder (PTSD) in prevention, treatment/or auxiliary treatment of PTSD, and screening of anti-PTSD medicines, and relates to applications of a compound with dopamine receptor D3R adjusting activity in preparation of medicines used for preventing, treatment and/or auxiliary treatment of PTSD.

CuI-catalyzed one-pot synthesis of benzothiazolones from 2-iodoanilines-derived carbamates and sodium sulfide

A copper-catalyzed procedure was developed for assembling benzothiazolones from ethyl 2-iodophenylcarbamates and sodium sulfide. A number of functional groups, such as methoxy, acyl, amide, carboxylate, trifluoromethyl, fluoro, and chloro, were tolerated under these conditions, providing benzothiazolones in good yields.

NOVEL DOPAMINE D3 RECEPTOR LIGANDS AND PREPARATION AND MEDICAL USES OF THE SAME

The present invention relates to a novel piperazine derivative represented by Formula I having an activity for regulating dopamine D3 receptor, stereoisomers thereof, pharmaceutically acceptable salts or solvates, and a pharmaceutical composition comprising the compound, a process for preparing the same, and use thereof in the prevention or treatment of a disease associated with central nervous system dysfunction, such as Parkinson''s disease, schizophrenia, drug addiction and relapse, as well as kidney protection and immunoregulation, or as a tool for researching D3R function or diseases associated with D3R dysfunction.