99686-98-3

Basic information

• Product Name: 2,3-diphenylquinoline-4-carboxylic acid
• Synonyms: 2,3-diphenylquinoline-4-carboxylic acid
• CAS NO: 99686-98-3
• Molecular Weight: 325.367
• Mol File: 99686-98-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2,3-diphenylquinoline-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-diphenylquinoline-4-carboxylic acid(99686-98-3)
• EPA Substance Registry System: 2,3-diphenylquinoline-4-carboxylic acid(99686-98-3)

Safety Data

• Hazardous Substances Data: 99686-98-3(Hazardous Substances Data)

Upstream product

• 156-06-9 2-oxo-3-(phenyl)propionic acid 
• 100-52-7 benzaldehyde 
• 62-53-3 aniline 
• 451-40-1 phenyl benzyl ketone 
• 91-56-5 indole-2,3-dione 

Downstream Products

• 30081-52-8 2,3-diphenyl-quinoline-4-carbonyl chloride 
• 30081-49-3 methyl 2,3-diphenylquinoline-4-carboxylate 
• 1298069-39-2 C₂₈H₂₀N₂O 
• 1298069-40-5 C₂₃H₁₈N₂O 
• 30081-50-6 2,3-diphenylquinoline-4-carboxamide 
• 30081-53-9 6-phenyl-indeno[1,2-c]quinolin-11-one 

Relevant articles and documents

Synthesis of some 2-aryl- and 2,3-diaryl-quinolin-4-carboxylic acid derivatives

Eighteen 2-aryl- and 2,3-diaryl-quinolin-4-carboxlic acid derivatives were synthesized. Basically, the synthetic design of these compounds arose from the appropriate disconnections of the target compounds, which revealed pyruvic acid, aromatic amine, and benzaldehyde or phenyl pyruvic acid, aromatic amine, and benzaldehyde as possible logical precursors for 2-aryl- and 2,3-aryl-quinolin-4- carboxylic acids respectively. The purity and identities of the synthesized compounds were elucidated through chromatographic and spectroscopic techniques (ultraviolet, infrared, mass, 1H NMR, and 13C NMR). The prepared derivatives were screened for their antibacterial activity against the standard bacterial organisms B. subtilis, S. aureus, E. coli, and P. vulgaris. 2,3-Diphenyl-6-sulfanilamido-quinolin-4-carboxylic acid showed the highest activity against the four tested organisms.