99784-35-7

Upstream product

• 350255-13-9 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 
• 69177-83-9 3-O-benzyl-5,6-dideoxy-1,2-O-isopropylidene-6-nitro-α-D-xylo-hex-5-enofuranose 
• 100-39-0 benzyl bromide 
• 908142-25-6 1-2 O-isopropylidene 3-O-benzyl α(D)gluco-pentoaldofuranose 
• 23558-05-6 3-O-benzyl-1,2-O-isopropylidene-1,5-D-xylo-dialdofuranose 
• 99784-34-6 3-O-benzyl-5,6-dideoxy-1,2-O-isopropylidene-6-C-nitro-α-D-xylo-hexanofuranose 
• 41545-33-9 3-O-benzyl-6-deoxy-1,2-O-isopropylidene-6-C-nitro-α-L-idofuranose 
• 86495-59-2 (E)-3-O-benzyl-5,6-dideoxy-1,2-O-isopropylidene-6-nitro-α-D-xylo-hex-5-eno-1,4-furanose 

Downstream Products

• 1606127-94-9 C₁₄H₁₄F₃NO₈S 
• 1606127-93-8 C₁₃H₁₅NO₆ 
• 99784-38-0 (3R,4R)-3-(benzyloxy)-4-(formyloxy)-1-nitro-1-cyclopentene 
• 99784-37-9 (1R,2R)-2-(benzyloxy)-3-hydroxy-5-nitrocyclopentan-1-ol 
• 99784-39-1 (3R,4R)-3-Benzyloxy-4-hydroxy-cyclopentanone 
• 99784-40-4 (4R)-4-(benzyloxy)-2-cyclopentenone 
• 99784-36-8 (2S,3R)-2-(benzyloxy)-3-(formyloxy)-5-nitropentanal 

Relevant academic research and scientific papers

Chain-Branched polyhydroxylated Octahydro-1H-Indoles as potential leads against lysosomal storage diseases

Here, the synthesis and glycosidase inhibition properties of the two first known 3-ethyloctahydro-1H-indole-4,5,6-triols are reported. This study shows the transformation of D-glucose into polyhydroxylated 1-(2-nitrocyclohexane) acetaldehydes, followed by a protocol involving the formation of the azacyclopentane ring. Results of inhibitory potency assays and docking calculations show that at least one of them could be a lead for optimization in the search for compounds that behave like folding chaperones in lysosomal storage diseases.

Stereocontrolled transformation of nitrohexofuranoses into cyclopentylamines via 2-oxabicyclo[2.2.1]heptanes. Part 6: Synthesis and incorporation into peptides of the first reported 2,3- dihydroxycyclopentanecarboxylic acid

Herein we report the intramolecular alkylation of nitronates of methyl-5-O-benzyl-3,6-deoxy-6-nitro-β-d-glucofuranoside and methyl-5-O-benzyl-3,6-deoxy-6-nitro-α-d-glucofuranoside into the corresponding 2-oxabicyclo[2.2.1]heptane derivatives. Similarly, m

Glycosynthase-Mediated Assembly of Xylanase Substrates and Inhibitors

An exo-β-xylosidase mutant with glycosynthase activity was created to aid in the synthesis of xylanase substrates and inhibitors. Simple monosaccharides were easily elaborated into di-, tri- and tetrasaccharides by using this enzyme. Some products proved