99809-38-8

Basic information

• Product Name: 2-methyl-6-<(p-tolylsulfonylfonyl)methyl>-4H-pyran-4-one
• CAS NO: 99809-38-8
• Molecular Weight: 278.329
• Mol File: 99809-38-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-methyl-6-<(p-tolylsulfonylfonyl)methyl>-4H-pyran-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-6-<(p-tolylsulfonylfonyl)methyl>-4H-pyran-4-one(99809-38-8)
• EPA Substance Registry System: 2-methyl-6-<(p-tolylsulfonylfonyl)methyl>-4H-pyran-4-one(99809-38-8)

Safety Data

• Hazardous Substances Data: 99809-38-8(Hazardous Substances Data)

Upstream product

• 99809-37-7 2-(bromomethyl)-6-methyl-4H-pyran-4-one 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 34241-51-5 2-acetyl-5-hydroxy-3-oxo-4-hexanoic acid δ-lactone 
• 1004-36-0 2,6-dimethylpyrone 

Downstream Products

• 99809-42-4 2-[2-(1,4-Dioxa-spiro[4.5]dec-6-yl)-1-(toluene-4-sulfonyl)-ethyl]-6-methyl-pyran-4-one 
• 99809-45-7 1-(1,4-Dioxa-spiro[4.5]dec-6-yl)-7-hydroxy-octan-3-one 
• 56150-33-5 2-methyl-6-phenethyl-4H-pyran-4-one 
• 99809-41-3 2-Methyl-6-[2-(2-oxo-cyclohexyl)-1-(toluene-4-sulfonyl)-ethyl]-pyran-4-one 
• 99809-39-9 2-methyl-6-<1-(p-tolylsulfonyl)-2-phenylethyl>-4H-pyran-4-one (8) 

Relevant articles and documents

Pyran Annelation: An Effective Route to a Tricyclic Dienone

A new pyran annelation reaction was investigated. 2,6-Dimethyl-4H-pyran-4-one (2) was converted to 2((p-tolylsulfonyl)methyl)-6-methyl-4H-pyran-4-one (7) which was alkylated at the C-2 methylene position regioselectively, and the p-tolylsulfonyl group can be easily eliminated with an aluminium amalgam reduction.On the other hand the pyran-4-one ring was easily transformed into an 1,5-diketone derivative.By joining and applying these selective alkylations and transformations, tricyclic dienone 22 was effectively synthesized from 2.