99809-45-7

Upstream product

• 99809-51-5 (E)-8-(1,4-Dioxa-spiro[4.5]dec-6-yl)-4-methylsulfanyl-oct-4-ene-2,6-dione 
• 1004-36-0 2,6-dimethylpyrone 
• 99809-37-7 2-(bromomethyl)-6-methyl-4H-pyran-4-one 
• 99809-43-5 2-<2-<2,2-(ethylenedioxy)cyclohexyl>etyl>-6-methyl-4H-pyran-4-one 
• 99809-44-6 2-[2-(1,4-Dioxa-spiro[4.5]dec-6-yl)-ethyl]-6-methyl-pyran-4-thione 
• 99809-38-8 2-methyl-6-<(p-tolylsulfonylfonyl)methyl>-4H-pyran-4-one 
• 99809-41-3 2-Methyl-6-[2-(2-oxo-cyclohexyl)-1-(toluene-4-sulfonyl)-ethyl]-pyran-4-one 
• 99809-42-4 2-[2-(1,4-Dioxa-spiro[4.5]dec-6-yl)-1-(toluene-4-sulfonyl)-ethyl]-6-methyl-pyran-4-one 
• 99809-50-4 2-[2-(1,4-Dioxa-spiro[4.5]dec-6-yl)-ethyl]-6-methyl-4-methylsulfanyl-pyranylium; iodide 
• 34241-51-5 2-acetyl-5-hydroxy-3-oxo-4-hexanoic acid δ-lactone 

Relevant academic research and scientific papers

Pyran Annelation: An Effective Route to a Tricyclic Dienone

A new pyran annelation reaction was investigated. 2,6-Dimethyl-4H-pyran-4-one (2) was converted to 2((p-tolylsulfonyl)methyl)-6-methyl-4H-pyran-4-one (7) which was alkylated at the C-2 methylene position regioselectively, and the p-tolylsulfonyl group can be easily eliminated with an aluminium amalgam reduction.On the other hand the pyran-4-one ring was easily transformed into an 1,5-diketone derivative.By joining and applying these selective alkylations and transformations, tricyclic dienone 22 was effectively synthesized from 2.