99838-00-3

Upstream product

• 67-68-5 dimethyl sulfoxide 
• 621-82-9 Cinnamic acid 
• 2373-51-5 chloro-methylsulfanyl-methane 
• 140-10-3 (E)-3-phenylacrylic acid 
• 77646-06-1 methylpedicinin 
• 108-24-7 acetic anhydride 
• 105376-26-9 3-cinnamoyl-2-hydroxy-5-methoxy-1,4-benzoquinone 
• 105342-76-5 2',3',5',6'-tetramethoxychalcone 
• 105342-75-4 3'-hydroxy-2',5',6'-trimethoxychalcone 
• 100-52-7 benzaldehyde 

Relevant academic research and scientific papers

Facile synthesis of methylthiomethyl esters through Pummerer-type rearrangement of carboxylic acids and DMSO under metal-free conditions

A green and cost-effective Pummerer-type rearrangement between readily accessible carboxylic acids and DMSO has been achieved under metal-free conditions in satisfactory to excellent yields. The transformation for the synthesis of valuable methylthiomethy

Synthetic method of methylthiomethyl

The invention provides a synthetic method of methylthiomethyl. The synthetic method comprises the step of carrying out crossed dehydrogenation on a carboxylic acid compound and dimethylsulfoxide in the presence of nitrogen and organic amine, so as to gene

A direct conversion of carboxylic acids to methylthiomethyl esters using a microwave-assisted pummerer rearrangement with dimethylsulfoxide

A simple microwave-assisted method for the conversion of carboxylic acids to MTM esters is presented. This new process allows for rapid introduction of an MTM ester protecting group to a variety of carboxylic acids including alkyl, electron-rich aromatic,

A simple, rapid and efficient protocol for the synthesis of methylthiomethyl esters under Swern oxidation conditions

A rapid, mild and high yielding method for the synthesis of methylthiomethyl esters is reported from the corresponding aliphatic, aromatic and unsaturated carboxylic acids under Swern oxidation conditions using dimethylsulfoxide, oxalyl chloride and triet

Synthesis of Manwuweizic acid, an anticancer triterpenoid

Manwuweizic acid (1), an anticancer triterpenoid isolated from Scisandra propinqua, was synthesized from lanosterol (2) by stereoselective introduction of the (Z) α,β-unsaturated carboxylic terminal of the side chain and by abnormal Beckmann rearrangement

Oxidative Rearrangement of Quinochalcones. Part 2. A Facile Synthesis of Linderone

Friedel-Crafts acylation of 1,2,3,5-tetramethoxybenzene in diethyl ether afforded besides the acetophenone (6a), an abnormal product shown to be 3-ethoxy-2-hydroxy-4,6-dimethoxy-acetophenone (6b).Methylpedicinin (1b), prepared from compoumd (6a), was foun

t-Butyl Bromide-Dimethyl Sulphoxide Reactions. Pummerer-like Reaction with Carboxylic Acids and N-Protected Amino-acids

t-Butyl bromide-activated dimethyl sulphoxide reacted with carboxylic acids and differently N-protected amino-acids in the presence of a base (NaHCO3 or Et3N).High to quantitative yields of methylthiomethyl (MTM) esters were obtained in all cases without interference by other functional groups or racemization.The mechanism of the reaction is discussed on the basis of the products formed, of spectral data, and of other miscellaneous experiments.