99839-30-2

Usage

Uses

Used in Chemical Reactions:
3-Bromo-4-chloro-pyridine 1-oxide is used as a building block in various chemical reactions for the synthesis of other compounds. Its unique structure allows for further functionalization and modification, making it a valuable intermediate in organic synthesis.
Used in Pharmaceutical Industry:
3-Bromo-4-chloro-pyridine 1-oxide is utilized in the pharmaceutical industry for the development of new drugs and therapeutics. Its versatile chemical properties enable the design and synthesis of novel drug candidates with potential therapeutic benefits.
Used in Organic Synthesis:
In the field of organic synthesis, 3-Bromo-4-chloro-pyridine 1-oxide serves as a key intermediate for the preparation of various organic compounds. Its presence of bromine and chlorine atoms allows for selective reactions and transformations, facilitating the synthesis of complex organic molecules.
Used in Medicinal Chemistry:
3-Bromo-4-chloro-pyridine 1-oxide is employed in medicinal chemistry for the design and synthesis of bioactive molecules. Its unique structural features can be exploited to develop compounds with potential therapeutic applications, contributing to the discovery of new drugs and treatments for various diseases.

Upstream product

• 89364-04-5 3-bromo-4-nitropyridine 
• 626-55-1 3-Bromopyridine 
• 2402-97-3 3-bromopyridine N-oxide 
• 1678-49-5 3-Bromo-4-nitropyridine N-oxide 

Downstream Products

• 1086277-95-3 3-[(3-bromo-pyridin-N-oxide-4-yl)oxyl]-4-(difluoromethoxy)benzaldehyde 
• 1086277-98-6 3-[(3-bromo-pyridin-N-oxide-4-yl)oxy]-4-(cyclopentyloxy)benzaldehyde 
• 1427158-11-9 3-bromo-4-[(4-methoxybenzyl)amino]pyridine-2-carbonitrile 
• 1427158-13-1 4-[(4-methoxybenzyl)amino]-3-sulfanylpyridine-2-carbonitrile 
• 1427158-12-0 3-bromo-N-(4-methoxybenzyl)[1,2]thiazolo[4,5-b]pyridin-7-amine 
• 1427158-53-9 N⁷-(4-methoxybenzyl)isoxazolo[4,5-b]pyridine-3,7-diamine 
• 1427158-14-2 N⁷-(4-methoxybenzyl)-N³-[4-(trifluoromethyl)phenyl][1,2]thiazolo[4,5-b]pyridine-3,7-diamine 
• 1427158-58-4 2-chloro-6-fluoro-N-(3-{[4-(trifluoromethyl)phenyl]amino}[1,2]thiazolo[4,5-b]pyridin-7-yl)benzamide 
• 1427158-59-5 2-chloro-5-{[(2,2-dimethylpropanoyl)amino]methyl}-N-(3-{[4-(trifluoromethyl)phenyl]amino}[1,2]thiazolo[4,5-b]pyridin-7-yl)benzamide 
• 1427263-56-6 C₂₁H₁₅ClF₃N₅OS 
• 1427158-60-8 2-chloro-5-((1-methylcyclopropanecarboxamido)methyl)-N-(3-((4-(trifluoromethyl)phenyl)amino)isothiazolo[4,5-b]pyridin-7-yl)benzamide 
• 1427158-09-5 N³-[4-(trifluoromethyl)phenyl][1,2]thiazolo[4,5-b]pyridine-3,7-diamine 
• 1427158-71-1 5-(aminomethyl)-2-chloro-N-(3-((4-(trifluoromethyl)phenyl)amino)isothiazolo[4,5-b]pyridin-7-yl)benzamide hydrochloride 
• 1427158-70-0 (R)-N-(4-chloro-3-((3-((4-(trifluoromethyl)phenyl)amino)isothiazolo[4,5-b]pyridin-7-yl)carbamoyl)benzyl)tetrahydrofuran-2-carboxamide 

Relevant academic research and scientific papers

SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS AS mPGES-1 INHIBITORS

The present invention relates to bicyclic compounds of formula (I) or pharmaceutically acceptable salt thereof as mPGES-1 inhibitors. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (m PGES-1) enzyme and are therefore useful in the treatment of pain and/or inflammation from a variety of diseases or conditions, such as asthama, osteoarthritis, rheumatoid arthritis, acute or chronic pain and neurodegenerative diseases. (I)

NOVEL PROCESSES FOR PREPARING 6-(DIFLUOROMETHOXY) [1]BENZOFURO[3,2-C]PYRIDINE-9-CARBALDEHYDE, A NOVEL INTERMEDIATE FOR THE SYNTHESIS OF PDE IV INHIBITORS

The present invention relates to novel processes for preparing 6-(difluoromethoxy)[1] benzofuro[3,2-c]pyridine-9-carbaldehyde, which is a novel and useful intermediate for preparing compounds with PDE4 inhibitory activity, such as 3,5-dichloro-4-(6- difluoromethoxybenzo[4,5] furo [3,2-c]pyridin-9-ylcarboxamido)-1 -pyridiniumolate