99845-84-8

Upstream product

• 1011266-01-5 C₁₁H₁₀O 
• 2142-69-0 2-bromophenyl methyl ketone 
• 107-18-6 allyl alcohol 
• 120254-80-0 1-bromo-2-(1,1-dimethoxyethyl)benzene 
• 6630-33-7 ortho-bromobenzaldehyde 
• 98-86-2 acetophenone 

Relevant academic research and scientific papers

Organocatalytic regiospecific synthesis of 1H-indene-2-carbaldehyde derivatives: suppression of cycloolefin isomerisation by employing sterically demanding catalysts

The regiospecific synthesis of 1H-indene-2-carbaldehyde derivatives was achieved through transition-metal-free, reductive cyclisation of ortho-formyl trans-cinnamaldehydes with Hantzsch ester in the presence of an aminocatalyst. In particular, cycloolefin isomerisation of the resulting products could be inhibited efficiently by the introduction of a sterically demanding stereo-defined aminocatalyst.

Rh(iii)-catalyzed dehydrogenative alkylation of (hetero)arenes with allylic alcohols, allowing aldol condensation to indenes

Efficient Rh(iii)-catalyzed C-H activation of different classes of (hetero)arenes such as 2-phenylpyridine, indoles, aryl ketones and acetanilide and their dehydrogenative cross-coupling with allylic alcohols are described. Several important skeletons suc

Studies on the synthesis of 2-acyl-1H-indenes via one-pot palladium-catalysed tandem Heck-aldol reaction

2-Acyl-1H-indenes were synthesised efficiently by the reaction of o-halogenatedbenzaldehydes (or aryl ketones) with prop-2-en-1-ols via one-pot palladium-catalysed tandem Heck-aldol reaction in moderate to good yields. The optimal reaction conditions have

Direct carbocyclization of aldehydes with alkynes: Combining gold catalysis with aminocatalysis

A combination of gold(l) complexes and amine bases catalyzes the 5-exo-dig cyclization of formyl alkynes. This direct α-functionalization of aldehydes with unactivated alkynes does not involve the use of preformed enol equivalents.