99847-13-9

Basic information

• Product Name: 3'-Nitro-biphenyl-4-carboxylic acid
• Synonyms: 3'-Nitro-biphenyl-4-carboxylic acid
• CAS NO: 99847-13-9
• Molecular Formula: C₁₃H₉NO₄
• Molecular Weight: 243.21486
• Mol File: 99847-13-9.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3'-Nitro-biphenyl-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-Nitro-biphenyl-4-carboxylic acid(99847-13-9)
• EPA Substance Registry System: 3'-Nitro-biphenyl-4-carboxylic acid(99847-13-9)

Safety Data

• Hazardous Substances Data: 99847-13-9(Hazardous Substances Data)

Upstream product

• 42087-80-9 methyl 4-chloro-2-nitrobenzoate 
• 98-80-6 phenylboronic acid 
• 154605-88-6 methyl 2-nitro-4-phenylbenzoate 
• 99277-71-1 4-bromo-2-nitrobenzoic acid 
• 2113-58-8 3-nitro-1,1'-biphenyl 
• 515878-88-3 3-nitro-biphenyl-4-carbaldehyde 
• 158580-57-5 methyl 4-bromo-2-nitrobenzoate 
• 106166-59-0 3-nitro-biphenyl-4-carboxylic acid amide 
• 99419-89-3 3-nitro-biphenyl-4-carbonitrile 

Downstream Products

• 887242-95-7 1,1-dimethylethyl (2S)-cyclohexyl-{[(3-nitro-4-biphenylyl)carbonyl]amino}-ethanoate 
• 1447083-18-2 C₁₈H₁₄BrNO₄S₂ 
• 1431382-12-5 C₁₇H₁₂BrNO₄S₂ 
• 515878-89-4 3-nitro-biphenyl-4-carboxylic acid [3-methoxy-4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amide 
• 515878-90-7 3-amino-biphenyl-4-carboxylic acid [3-methoxy-4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amide 
• 4445-43-6 3-amino-[1,1'-biphenyl]-4-carboxylic acid 
• 1352638-16-4 3-nitrobiphenyl-4-carboxylic acid (3,4-dihydroxy-5-methoxyphenyl)amide 
• 1352637-93-4 3-nitrobiphenyl-4-carboxylic acid (3,4,5-trimethoxyphenyl)amide 
• 100965-88-6 3-nitro-7-phenyl-quinolin-4-ol 
• 108618-34-4 3-amino-7-phenyl-quinolin-4-ol 

Relevant articles and documents

Copper-catalyzed oxidative decarboxylative C-H arylation of benzoxazoles with 2-nitrobenzoic acids

A copper-catalyzed oxidative decarboxylative coupling of benzoxazoles with 2-nitrobenzoic acids was developed. This methodology favors electron-rich benzoxazoles and electron-deficient benzoic acids and enables the preparation of a variety of arylated benzoxazoles in good yields. The trends in product yields suggest a delicate balance between the decarboxylation and C-H arylation steps.

Potent galloyl-based selective modulators targeting multidrug resistance associated protein 1 and P-glycoprotein

The multifactorial nature of chemotherapy failure in controlling cancer is often associated with the occurrence of multidrug resistance (MDR), a phenomenon likely related to the increased expression of members of the ATP binding cassette (ABC) transporter superfamily. In this respect, the most extensively characterized MDR transporters include ABCB1 (also known as MDR1 or P-glycoprotein) and ABCC1 (also known as MRP1) whose inhibition remains a priority to circumvent drug resistance. Herein, we report how the simple galloyl benzamide scaffold can be easily and properly decorated for the preparation of either MRP1 or P-gp highly selective inhibitors. In particular, some gallamides and pyrogallol-1-monomethyl ethers showed remarkable affinity and selectivity toward MRP1. On the other hand, trimethyl ether galloyl anilides, with few exceptions, exhibited moderate to very high and selective P-gp inhibition.

GLYCOGEN PHOSPHORYLASE INHIBITOR COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF

The invention relates to glycogen phosphorylase inhibitor compounds, pharmaceutical compositions of these compounds, methods of treatment using the pharmaceutical compositions to treat diabetes, conditions associated with diabetes, and/or tissue ischemia,