99847-70-8

Usage

Uses

Used in Biological Research:
IFLAB-BB F2124-0403 is used as a fluorescent marker for deep-tissue imaging, allowing researchers to visualize cellular structures and processes with reduced background fluorescence and high contrast.
Used in Imaging Applications:
IFLAB-BB F2124-0403 is used as a near-infrared fluorophore for long-term imaging studies, providing high-resolution images and strong photo-resistance, which is ideal for observing complex biological systems over extended periods.
Used in Cellular Tracking:
IFLAB-BB F2124-0403 is used as a labeling agent for tracking cellular structures, offering compatibility with various labeling techniques and enabling the visualization of cellular processes in detail.
Used in Visualization of Cellular Processes:
IFLAB-BB F2124-0403 is used as a tool for visualizing cellular processes, providing high contrast and resolution in imaging experiments, which aids in the study of complex biological systems.

Upstream product

• 1075-34-9 5-bromo-2-methyl-1H-indole 
• 267002-57-3 2-allyl-4-bromoaniline 
• 106-40-1 4-bromo-aniline 
• 22774-76-1 N-allyl-4-bromobenzenamine 

Downstream Products

• 101118-51-8 1-benzoyl-5-bromo-2-methyl-indoline 
• 1075-34-9 5-bromo-2-methyl-1H-indole 

Relevant academic research and scientific papers

SULFONYL-SUBSTITUTED BICYCLIC COMPOUND WHICH ACTS AS ROR INHIBITOR

Provided is a sulfonyl-substituted bicyclic compound (A) which acts as a RORγ inhibitor, said compound has good RORγ inhibitory activity and is expected to be used for treating diseases mediated by a RORγ receptor in mammals.

Kinetic resolutions of lndolines by a nonenzymatic acylation catalyst

The first method for the kinetic resolution of indolines through catalytic N-acylation is described. To improve the selectivity factor, new planar-chiral PPY-derived catalysts were synthesized, wherein the chiral environment was systematically modified. This work provides a rare example of a nonenzyme-based acylation catalyst for the kinetic resolution of amines. Copyright

Novel strategies for the solid phase synthesis of substituted indolines and indoles

Using a polymer-bound selenenyl bromide resin, o-allyl and o-prenyl anilines were cycloaded to afford a series of solid-supported indoline and indole scaffolds. These scaffolds were then functionalized and cleaved via four distinct methods, namely traceless reduction, radical cyclization, radical rearrangement, and oxidative elimination, to afford 2-methyl indolines, polycyclic indolines, 2-methyl indoles, and 2-propenyl indolines, respectively. A number of small combinatorial libraries of compounds reminiscent of certain designed ligands of biological interest were constructed demonstrating the potential utility of the developed methodology to chemical biology studies and the drug discovery process.

A Mild and Selective C-3 Reductive Alkylation of Indoles

In the presence of triethylsilane and trifluoroacetic acid, the reaction between indoles and aldehydes in dichloromethane at 0 deg C, results in good yields of C-3 reductively alkylated products.The transformation is most effective for the preparation of 3-(arylmethyl)indoles 6 from aromatic aldehydes.