99876-71-8Relevant academic research and scientific papers
Angiotensin converting enzyme inhibitors. 10. Aryl sulfonamide substituted N-[1-carboxy-3-phenylpropyl]-L-alanyl-L-proline derivatives as novel antihypertensives
Mencel,Regan,Barton,Menard,Bruno,Calvo,Kornberg,Schwab,neiss,Suh
, p. 1606 - 1615 (1990)
Compounds 1a-g consisting of enalaprilat covalently bonded to aryl sulfonamides, including several known thiazide diuretics, were synthesized and tested for ACE inhibitory and diuretic and overall antihypertensive effects. All compounds were potent ACE in
