99997-51-0

Upstream product

• 501-53-1 benzyl chloroformate 
• 63-91-2 L-phenylalanine 
• 138228-90-7 methyl 2-[((2S)-2-[[(benzyloxy)carbonyl]amino]-3-phenylpropanoyl)(methyl)amino]acetate 
• 1161-13-3 N-Cbz-L-Phe 

Downstream Products

• 138228-93-0 N²-<(benzyloxy)carbonyl>-N¹-(methoxymethyl)-N¹-methyl-L-phenylalaninamide 
• 138229-12-6 diphenyl 2.1-<(benzyloxy)carbonyl>-L-phenylalanyl-(2,2-decarboxy-N^2.2-methyl-L-phenylalanin-2,2-yl)>phosphonate 
• 138229-12-6 diphenyl 2.1-<(benzyloxy)carbonyl>-L-phenylalanyl-(2,2-decarboxy-N^2.2-methyl-D-phenylalanin-2,2-yl)>phosphonate 
• 138229-06-8 diphenyl 2.1-<(benzyloxy)carbonyl>-L-phenylalanyl-(2,2-decarboxy-N^2.2-methyl-3,2-vinyl-L-alanin-2,2-yl)>phosphonate 
• 138229-06-8 diphenyl 2.1-<(benzyloxy)carbonyl>-L-phenylalanyl-(2,2-decarboxy-N^2.2-methyl-3,2-vinyl-D-alanin-2,2-yl)>phosphonate 
• 138228-96-3 diphenyl N^2.1-<(benzyloxy)carbonyl>-L-phenylalanyl-(2,2-decarboxysarcosin-2,2-yl)phosphonate 
• 107-97-1 sarcosine 
• 1161-13-3 N-Cbz-L-Phe 

Relevant academic research and scientific papers

Influence of solvent viscosity on the rate of hydrolysis of dipeptides by carboxypeptidase Y

The influence of solvent viscosity on the rate of enzymatic hydrolysis of a series of dipeptides (Z-Phe-Gly, Z-Phe-Sar, Z-Phe-Ala, Z-Phe-NMeAla, Z-Phe-Aib and Z-Phe-Pro) by carboxypeptidase Y was investigated. The effect of solvent viscosity on the enzymatic hydrolysis revealed that whereas all Kcat values decreased with viscosity, those of the N-alkyl peptides decreased more than those of the N-H peptides. The kinetic behaviour implies the involvement of conformational changes of the enzyme in terms of the 'induced-fit' process. Copyright