458-37-7 Curcumin C21H20O6 CAS NO.458-37-7

Min.Order Quantity:: 1 Kilogram

Purity:: 99%

Port:: any port in China

Payment Terms:: L/C,T/T,

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Product Details

Keywords

458-37-7
Curcumin
C21H20O6

Quick Details

ProName: 458-37-7 Curcumin C21H20O6
CasNo: 458-37-7
Molecular Formula: C21H20O6
Appearance: white powder
Application: 458-37-7
DeliveryTime: Within 7 days after order confirmed
PackAge: normal package
Port: any port in China
ProductionCapacity: 1 Metric Ton/Day
Purity: 99%
Storage: 2-6℃
Transportation: by air
LimitNum: 1 Kilogram
Grade: Industrial Grade,Food Grade,Pharma Gra...

Superiority

our company was built in 2009 with an iso certificate.in the past 8 years, we have grown up as a famous fine chemicals supplier in china and we had established stable business relationships with samsung,lg,merck,thermo fisher scientific and so on.our main business covers the fields below:

1.noble metal catalysts (pt.pd...)

2.organic phosphine ligands (tert-butyl-phosphine.cyclohexyl-phosphine...)

3.oled intermediates (fluorene,carbazole,boric acid...)

4.customs synthesis

our advantage:

1. higest quality and good package

2.fast delivery

3.better payment term

4.fast response to customer within 6 hours

5.good business credit in europe ,us ,japan ,korea

anyway ,if you need any chemicals from china ,henan tianfu can help you

Details

curcumin basic information

product name:	curcumin
synonyms:	curcumin, natural yellow 3, diferuloylmethane;curcumin 1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione;curcumin solution ;curcumin, curcuma longa (high purity);curcuimn;curcumin from curcuma longa crystall;curcumin (mixture of curcumin;turmeric extract
cas:	458-37-7
mf:	c21h20o6
mw:	368.38
einecs:	207-280-5
product categories:	phytochemical;reference standards from chinese medicinal herbs (tcm).;standardized herbal extract;diferuloylmethane, natural yellow 3, c.i. 75300;pigment;miscellaneous natural products;analytical chemistry;antioxidant;biochemistry;indicator (ph);ph indicators;colorants;natural plant extract;aromatics;inhibitors;intermediates & fine chemicals;pharmaceuticals;chemical reagent;pharmaceutical intermediate;chalcone;miscellaneous
mol file:	458-37-7.mol

curcumin chemical properties

melting point	183 °c
density	0.93
vapor density	13 (vs air)
refractive index	1.4155-1.4175
fp	14℃
storage temp.	−20°c
solubility	ethanol: 10 mg/ml
form	powder
pka	8.09(at 25℃)
colour index	75300
color	orange
ph range	yellow (7.8) to red-brown (9.2)
water solubility	slightly soluble (hot)
λmax	430nm
merck	14,2673
brn	2306965
stability:	stable, but may be light sensitive. incompatible with strong oxidizing agents.
major application	cosmetics, drug-eluting stents, inhibition of formation of skin-wrinkles, treating alzheimer’s disease, skin diseases, coronary restenosis, diabetes, obesity, leukemia, neurofibromas, cancer, antimicrobial, antiviral, antiinflammatory, antiprostate cancer
cas database reference	458-37-7(cas database reference)
epa substance registry system	1,6-heptadiene-3, 5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, (1e,6e)-(458-37-7)

safety information

hazard codes	xi,f
risk statements	36/37/38-11
safety statements	26-36-16-7-37/39
ridadr	un1170 - class 3 - pg 2 - ethanol, solution
wgk germany	2
rtecs	mi5230000
hazard note	irritant
tsca	yes
hs code	29145000
hazardous substances data	458-37-7(hazardous substances data)

msds information

provider	language
c.i. 75300	english

curcumin usage and synthesis

chemical properties	orange crystalline powder
uses	a natural phenolic compound. potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase c (pkc) activity. reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. potent inhibitor of egfr tyrosine kinase and iκb kinase. inhibits inducible nitric oxide synthase (inos), cycloxygenase and lipoxygenase. easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.
uses	antiedemic, antiinflammatory, bile stimulant; antibacterial, antifungal, lipo/cyclooxygenase inhibitor
uses	curcumin is the principal curcuminoid of the popular indian spice turmeric, which is a member of the ginger family (zingiberaceae). the curcuminoids are polyphenols and are responsible for the yellow color of turmeric. curcumin can exist in at least two t
definition	chebi: a beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. a natural dyestuff found in the root of curcuma longa.
general description	orange-yellow needles.
air & water reactions	slightly soluble in hot water .
reactivity profile	curcumin is sensitive to light and changes in ph. curcumin may react with oxidizing materials.
biological activity	antitumor, anti-inflammatory and antioxidant agent. downregulates expression of reactive-oxygen-generating enzymes (cyclooxygenase, lipoxygenase, inos), tnf α , il-1, il-6, pkc, egfr, nf- κ b, i κ b kinase and more. upregulates expression of ppar γ , p53, nrf2. also displays antimicrobial, antidiabetic neuro- and cardioprotective properties in vivo .