Estradiol hemihydrate EP ≥97.5% API Hormone made in china CAS NO.35380-71-3

appearance

white or almost white, crystalline powder or colourless crystals

solubility

practically insoluble in water, soluble in acetone, sparingly soluble in alcohol, slightly soluble in ether and in methylene chloride

identification

a：ir b：tlc c：positive

specific optical rotation

+76.0°～ +83.0°

melting range

175～180℃

water

2.9%～3.5%

related substance

impurity a ≤ 0.3%

impurity b ≤ 0.3%

impurity c ≤ 0.3%

impurity d ≤ 0.3%

total impurities ≤ 0.5%

any other impurity ≤ 0.1%

residual solvents

alcohol≤0.5%

assay

97.0～103.0% (on the dried basis)