Rifapentine CAS NO.61379-65-5

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a review of alternative regimens for prevention of active tuberculosis in hiv-negative individuals with latent tb found that a weekly, directly observed regimen of rifapentine with isoniazid for three months was as effective as a daily, self -administered regimen of isoniazid for nine months. but the rifapentine-isoniazid regimen had higher rates of treatment completion and lower rates of hepatotoxicity. however, the rate of treatment-limiting adverse events was higher in the rifapentine-isoniazid regimen.