Supply 69-52-3 Ampicillin sodium in stock/69-52-3 manufacturer CAS NO.69-52-3

ampicillin sodium

supply 69-52-3 ampicillin sodium in stock/69-52-3 manufacturer

description:

sulbactam sodium salt is a beta-lactamase inhibitor that has similar characteristics as ampicillin.

product name: ampicillin sodium

other name: sodium [2s-[2alpha,5alpha,6beta(s*)]]-6-(aminophenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;d-(-)-alpha-aminobenzylpenicillin sodium salt

cas no.: 69388-84-7

einecs no.: 273-984-4

mf: c8h10nnao5s

mw: 255.23

appearance:white or off white powder or crystal.

inchi: inchi=1/c8h11no5s.na/c1-8(2)6(7(11)12)9-4(10)3-5(9)15(8,13)14;/h5-6h,3h2,1-2h3,(h,11,12);/q;+1/t5-,6+;/m1./s1

melting point: >230 °c

assay:99%min

function:

ampicillin sodium is in the penicillin group of beta-lactam antibiotics and is part of the aminopenicillin family. it is roughly equivalent to amoxicillin in terms of activity.

ampicillin sodium is able to penetrate gram-positive and some gram-negative bacteria. it differs from penicillin g, or benzylpenicillin, only by the presence of an amino group. that amino group helps the drug penetrate the outer membrane of gram-negative bacteria.

ampicillin sodium acts as an irreversible inhibitor of the enzyme transpeptidase, which is needed by bacteria to make theircell walls.it inhibits the third and final stage of bacterial cell wall synthesis in binary fission, which ultimately leads to cell lysis; therefore ampicillin is usually bacteriolytic.

application:

ampicillin sodium is active against many gram-positive and gram-negative bacteria.

ampicillin sodium was the first 'broad spectrum' penicillin with activity against gram-(+) bacteria including streptococcus pneumoniae, streptococcus pyogenes, some isolates of staphylococcus aureus (but not penicillin-resistant or methicillin-resistant strains), and some enterococci. activity against gram-(−) bacteria includes neisseria meningitidis, somehaemophilus influenzae, and some enterobacteriaceae. its spectrum of activity is enhanced by co-administration ofsulbactam, a drug that inhibits beta lactamase, an enzyme produced by bacteria to inactivate ampicillin and related antibiotics.

ampicillin sodium is used for the treatment of infections known to be or highly likely to be caused by these bacteria. these include common respiratory infections including sinusitis, bronchitis, and pharyngitis, as well as otitis media. in combination with vancomycin (which provides coverage of ampicillin-resistant pneumococci), it is effective for the treatment of bacterial meningitis. it is also used for gastrointestinal infections caused by consuming contaminated water or food, such as salmonella, shigella, and listeriosis.

ampicillin sodium is a first-line agent for the treatment of infections caused by enterococci. the bacteria are an important cause of healthcare-associated infections such as endocarditis, meningitis, and catheter-associated urinary tract infections that are typically resistant to other antibiotics.