1086391-99-2Relevant articles and documents
Biocatalytic Routes to Enantiomerically Enriched Dibenz[c,e]azepines
France, Scott P.,Aleku, Godwin A.,Sharma, Mahima,Mangas-Sanchez, Juan,Howard, Roger M.,Steflik, Jeremy,Kumar, Rajesh,Adams, Ralph W.,Slabu, Iustina,Crook, Robert,Grogan, Gideon,Wallace, Timothy W.,Turner, Nicholas J.
, p. 15589 - 15593 (2017)
Biocatalytic retrosynthetic analysis of dibenz[c,e]azepines has highlighted the use of imine reductase (IRED) and ω-transaminase (ω-TA) biocatalysts to establish the key stereocentres of these molecules. Several enantiocomplementary IREDs were identified
Asymmetric Hydrogenation of Dibenzo[ c,e]azepine Derivatives with Chiral Cationic Ruthenium Diamine Catalysts
Zhang, Shanshan,Chen, Fei,He, Yan-Mei,Fan, Qing-Hua
supporting information, p. 5538 - 5541 (2019/08/01)
An efficient Ru-catalyzed asymmetric hydrogenation of dibenzo[c,e]azepines is reported. A series of seven-membered cyclic amines were obtained with moderate to excellent enantioselectivity. The catalyst counteranion played an important role in achieving high-level chiral induction. Moreover, a one-pot synthesis of chiral 6,7-dihydro-5H-dibenz[c,e]azepines via two-step reductive amination was also developed.
10A-AZALIDE COMPOUND HAVING 4-MEMBERED RING STRUCTURE
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Page/Page column 54, (2011/04/14)
A 10a-azalide compound having a 4-membered ring structure crosslinked at the 10a- and 12-positions, which is represented by the formula (I), and is effective on even Haemophilus influenzae, or erythromycin resistant bacteria (e.g., resistant pneumococci and streptococci).
TRIAZOLYL AMINOPYRIMIDINE COMPOUNDS
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, (2009/01/20)
The present invention provides triazolyl aminopyrimidine compounds useful in the treatment of cancer.