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5-Bromo-7-methoxyquinoline is a complex chemical compound that belongs to the class of organic compounds known as quinolines and derivatives. It is characterized by a bicyclic heterocycle structure, with a benzene ring fused to a pyridine ring, and features additional bromine and methoxy groups. As a brominated compound and a methoxyquinoline, it is primarily used in scientific research, particularly in the field of synthetic organic chemistry, for synthesizing more complex chemical structures. It is often stored as a pale to dark brown or light yellow powder or crystals.

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  • 1126824-44-9 Structure
  • Basic information

    1. Product Name: 5-broMo-7-Methoxyquinoline
    2. Synonyms: 5-broMo-7-Methoxyquinoline
    3. CAS NO:1126824-44-9
    4. Molecular Formula: C10H8BrNO
    5. Molecular Weight: 238.08062
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1126824-44-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 329.0±22.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.516±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
    8. Solubility: N/A
    9. PKA: 4.22±0.26(Predicted)
    10. CAS DataBase Reference: 5-broMo-7-Methoxyquinoline(CAS DataBase Reference)
    11. NIST Chemistry Reference: 5-broMo-7-Methoxyquinoline(1126824-44-9)
    12. EPA Substance Registry System: 5-broMo-7-Methoxyquinoline(1126824-44-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1126824-44-9(Hazardous Substances Data)

1126824-44-9 Usage

Uses

Used in Scientific Research:
5-Bromo-7-methoxyquinoline is used as a chemical intermediate for the synthesis of more complex chemical structures, particularly in the field of synthetic organic chemistry. Its unique structure and properties make it a valuable component in the development of new compounds and materials.
Used in Pharmaceutical Industry:
5-Bromo-7-methoxyquinoline is used as a building block in the synthesis of pharmaceutical compounds. Its presence in the molecular structure can influence the biological activity and properties of the final drug product, making it an important component in drug discovery and development.
Used in Chemical Synthesis:
5-Bromo-7-methoxyquinoline is used as a reagent in various chemical reactions, allowing for the creation of a wide range of chemical products. Its versatility in chemical synthesis makes it a valuable resource in the production of specialty chemicals and materials.
Used in Material Science:
5-Bromo-7-methoxyquinoline is used as a component in the development of new materials with specific properties, such as improved stability, reactivity, or selectivity. Its incorporation into material structures can lead to advancements in various industries, including electronics, coatings, and plastics.

Check Digit Verification of cas no

The CAS Registry Mumber 1126824-44-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,2,6,8,2 and 4 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1126824-44:
(9*1)+(8*1)+(7*2)+(6*6)+(5*8)+(4*2)+(3*4)+(2*4)+(1*4)=139
139 % 10 = 9
So 1126824-44-9 is a valid CAS Registry Number.

1126824-44-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Bromo-7-methoxyquinoline

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1126824-44-9 SDS

1126824-44-9Downstream Products

1126824-44-9Relevant articles and documents

Synthesis method of 7-bromo-5-methoxyquinoline

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Paragraph 0011; 0015; 0016, (2021/03/11)

The invention discloses a synthesis method of 7-bromo-5-methoxyquinoline, which comprises the following steps: carrying out Skraup condensation reaction on 3, 5-dibromoaniline serving as a raw material and glycerol to obtain 5, 7-dibromoquinoline, reacting with sodium methoxide to obtain 5-bromo-7-methoxyquinoline and 7-bromo-5-methoxyquinoline, and finally carrying out column chromatography purification and separation to obtain the 7-bromo-5-methoxyquinoline. The method overcomes the defects of low yield, microwave condition requirement, difficulty in post-treatment, difficulty in amplification and the like in the existing synthesis process. According to the synthetic method, the 3, 5-dibromoaniline is used as a raw material, the process selection is reasonable, the raw material cost is low, the raw materials are simple and easy to obtain, the operation and post-treatment are convenient, the total yield is high, a highly toxic reagent is not used, amplification is easy, and large-scale production can be carried out.

SUBSTITUTED QUINOLINES AND THEIR USE AS MEDICAMENTS

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Page/Page column 49, (2013/03/26)

The invention relates to new substituted quinolines of formula (1) wherein R1 is a linear or branched C1-6-alkyl, wherein R1 may optionally be substituted by R3 which is selected from the group consisting of a three-, four-, five-, six- or seven-membered cycloalkl; a five-, six- or seven-membered, saturated heterocycle comprising one, two or three heteroatoms each independently selected from the group consisting of N, S and O; and a five- or six-membered heteroaryl comprising one, two or three heteroatoms each independently selected from the group consisting of N, S and O; wherein R3 may optionally be substituted further substituted as defined in claim 1 and wherein R2 is selected from the group consisting of halogen, phenyl, a five- or six-membered monocyclic heteroaryl comprising one, two or three heteroatoms each independently selected from the group consisting of N, S and O; a bicyclic, nine-, ten- or eleven-membered, either aromatic or non-aromatic, but not fully saturated heterocycle comprising one, two, three or four heteroatoms each independently selected from the group consisting of N, S and O; wherein R2 may optionally be further substituted as defined in claim 1, and their use in the preparation of medicaments for the treatment of disease such as asthma, COPD, allergic rhinitis, allergic dermatitis and rheumatoid arthritis.

Substituted Quinolines and Their Use As Medicaments

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Paragraph 0119; 0120; 0121, (2013/03/26)

Disclosed are substituted quinolines of formula 1 wherein R1 and R2 are defined herein, the processing of making and using the same.

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