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CAS

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1197377-31-3

1-[2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidinedione is a chemical compound that is a derivative of pyrrolidinedione. It features a chloro and hydroxyl group attached to a quinolinyl-propyl chain, which contributes to its potential medicinal properties. 1-[2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidinedione is recognized for its unique chemical structure and properties, making it a valuable component in drug discovery and development.

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  • 1-[2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidinedione

    Cas No: 1197377-31-3

  • USD $ 1.9-2.9 / Gram

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  • 1197377-31-3 Structure

  • Basic information

    1. Product Name: 1-[2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidinedione
    2. Synonyms: 1-[2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidinedione;1-(2-chloro-1-hydroxy-3-(quinolin-6-yl)propyl)pyrrolidine-2,5-dione
    3. CAS NO:1197377-31-3
    4. Molecular Formula: C16H15ClN2O3
    5. Molecular Weight: 318.7549
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1197377-31-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 598.3±50.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.434±0.06 g/cm3(Predicted)
    6. Vapor Pressure: 0-0Pa at 20-25℃
    7. Refractive Index: N/A
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. PKA: 11.45±0.20(Predicted)
    11. CAS DataBase Reference: 1-[2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidinedione(CAS DataBase Reference)
    12. NIST Chemistry Reference: 1-[2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidinedione(1197377-31-3)
    13. EPA Substance Registry System: 1-[2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidinedione(1197377-31-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1197377-31-3(Hazardous Substances Data)

1197377-31-3 Usage

Uses

Used in Pharmaceutical Industry:
1-[2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidinedione is used as a pharmaceutical compound for its potential medicinal properties. It has been studied for its anti-inflammatory, analgesic, and anticonvulsant properties, which make it a promising candidate for the treatment of various medical conditions.
Used in Drug Discovery and Development:
In the field of drug discovery and development, 1-[2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidinedione is utilized as a key component due to its unique chemical structure and properties. Researchers are exploring its potential therapeutic applications, which could lead to the development of new medications for a range of health issues.
Used in Medical Research:
1-[2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidinedione is also used in medical research to investigate its potential as a treatment for various conditions. Its anti-inflammatory, analgesic, and anticonvulsant properties are being studied to understand how it may be applied to alleviate symptoms and improve patient outcomes.

Check Digit Verification of cas no

The CAS Registry Mumber 1197377-31-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,7,3,7 and 7 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1197377-31:
(9*1)+(8*1)+(7*9)+(6*7)+(5*3)+(4*7)+(3*7)+(2*3)+(1*1)=193
193 % 10 = 3
So 1197377-31-3 is a valid CAS Registry Number.

1197377-31-3Relevant articles and documents

Deuterated Capmatinib compounds and uses thereof

-

, (2019/12/25)

The invention discloses deuterated Capmatinib compounds and uses thereof, in particular to compounds represented by formula (I) or optical isomers, pharmaceutically acceptable salts, hydrate or solvate thereof, wherein R1-R16 is independently selected fro

Design, synthesis, and biological evaluation of novel imidazo[1,2-a]pyridine derivatives as potent c-met inhibitors

Li, Chunpu,Ai, Jing,Zhang, Dengyou,Peng, Xia,Chen, Xi,Gao, Zhiwei,Su, Yi,Zhu, Wei,Ji, Yinchun,Chen, Xiaoyan,Geng, Meiyu,Liu, Hong

, p. 507 - 512 (2015/05/27)

A series of imidazo[1,2-a]pyridine derivatives against c-Met was designed by means of bioisosteric replacement. In this study, a selective, potent c-Met inhibitor, 22e was identified, with IC50 values of 3.9 nM against c-Met kinase and 45.0 nM

IMIDAZO[1,2-B][1,2,4]TRIAZINES AS C-MET INHIBITORS

-

, (2011/09/20)

The present invention relates to imidazo[1,2-b][1,2,4]triazines that are inhibitors of c-Met and are useful in the treatment of c-Met associated diseases including cancer.

SALTS OF 2-FLUORO-N-METHYL-4-[7-(QUINOLIN-6-YL-METHYL)-IMIDAZO[1,2-b][1,2,4]TRIAZIN-2-YL]BENZAMIDE AND PROCESSES RELATED TO PREPARING THE SAME

-

Page/Page column 22; 23-24, (2009/12/05)

The present invention is directed to dihydrochloric acid and dibenzenesulfonic acid salts of the c-Met kinase inhibitor 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)-imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, and pharmaceutical compositions thereof, useful in the treatment of cancer and other diseases related to the dysregulation of kinase pathways. The present invention further relates to processes and intermediates for preparing 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, and salts thereof.

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