1489004-27-4 Usage
Uses
Used in Pharmaceutical Synthesis:
Trans-N-Boc-2-(4-chlorophenyl)-3-(isopropylamino) acrylic acid is used as a key intermediate in the synthesis of various pharmaceuticals. Its functional groups and reactivity make it a valuable building block for creating complex organic molecules with potential therapeutic applications.
Used in Bioactive Compound Preparation:
Trans-N-Boc-2-(4-chlorophenyl)-3-(isopropylamino) acrylic acid is utilized in the preparation of bioactive compounds, contributing to the development of new drugs and therapeutic agents. Its unique structure and functional groups enable it to participate in a range of chemical reactions, facilitating the synthesis of diverse bioactive molecules.
Used in Chemical Research:
Trans-N-Boc-2-(4-chlorophenyl)-3-(isopropylamino) acrylic acid is employed in chemical research to explore its properties and reactions. Its ability to undergo various chemical transformations makes it an interesting subject for studies aimed at understanding reaction mechanisms and developing new synthetic methodologies.
Used in Material Development:
Trans-N-Boc-2-(4-chlorophenyl)-3-(isopropylamino) acrylic acid is also used in the development of new materials, where its functional groups and reactivity can contribute to the creation of innovative materials with unique properties and applications across different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 1489004-27-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,8,9,0,0 and 4 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1489004-27:
(9*1)+(8*4)+(7*8)+(6*9)+(5*0)+(4*0)+(3*4)+(2*2)+(1*7)=174
174 % 10 = 4
So 1489004-27-4 is a valid CAS Registry Number.
1489004-27-4Relevant articles and documents
PROCESSES FOR THE PREPARATION OF PYRIMIDINYLCYCLOPENTANE COMPOUNDS
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, (2015/06/03)
The present invention relates to a process for the preparation of a compound of formula (I), wherein R1 is as defined herein, which is useful as an intermediate in the preparation of active pharmaceutical compounds.
An efficient catalytic asymmetric synthesis of a β2-amino acid on multikilogram scale
Remarchuk, Travis,Babu, Srinivasan,Stults, Jeffrey,Zanotti-Gerosa, Antonio,Roseblade, Stephen,Yang, Shaohui,Huang, Ping,Sha, Chunbo,Wang, Youchu
, p. 135 - 141 (2014/05/20)
We describe herein a scalable catalytic asymmetric hydrogenation process for the multikilogram-scale production of a β 2-amino acid. A short and efficient synthesis of the starting unsaturated N-Boc-protected β 2-enamide was developed followed by extensive catalysis screening and optimization studies that identified a simple Ru-BINAP catalyst system to directly afford the (S) product in high enantiomeric excess and yield. The final process enabled the multikilogram production in >99% ee, to be used as a key component for one of our clinical candidates.
PROCESS FOR MAKING AMINO ACID COMPOUNDS
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, (2013/12/03)
The invention provides new processes for making and purifying amino acid compounds, which are useful in the preparation of AKT inhibitors used in the treatment of diseases such as cancer, including the compound (S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one.
