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1001179-33-4

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1001179-33-4 Usage

General Description

The chemical "(S)-3-((tert-butoxycarbonyl)(isopropyl)amino)-2-(4-chlorophenyl)propionic acid" is a compound that consists of a 4-chlorophenyl group, an isopropylamino group, and a propionic acid group. It also contains a tert-butoxycarbonyl protective group. (S)-3-((tert-butoxycarbonyl)(isopropyl)amino)-2-(4-chlorophenyl)propionic acid is a chiral molecule with an S configuration, meaning it has a specific 3D arrangement of atoms. It is commonly used in organic chemistry as a building block for the synthesis of various pharmaceuticals, agrochemicals, and other biologically active compounds. This chemical has potential applications in the development of new drugs and treatments.

Check Digit Verification of cas no

The CAS Registry Mumber 1001179-33-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,1,1,7 and 9 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1001179-33:
(9*1)+(8*0)+(7*0)+(6*1)+(5*1)+(4*7)+(3*9)+(2*3)+(1*3)=84
84 % 10 = 4
So 1001179-33-4 is a valid CAS Registry Number.

1001179-33-4Relevant articles and documents

Asymmetric Synthesis of Akt Kinase Inhibitor Ipatasertib

Han, Chong,Savage, Scott,Al-Sayah, Mohammad,Yajima, Herbert,Remarchuk, Travis,Reents, Reinhard,Wirz, Beat,Iding, Hans,Bachmann, Stephan,Fantasia, Serena M.,Scalone, Michelangelo,Hell, André,Hidber, Pirmin,Gosselin, Francis

, p. 4806 - 4809 (2017/09/23)

A highly efficient asymmetric synthesis of the Akt kinase inhibitor ipatasertib (1) is reported. The bicyclic pyrimidine 2 starting material was prepared via a nitrilase biocatalytic resolution, halogen-metal exchange/anionic cyclization, and a highly dia

Synthesis of Akt inhibitor ipatasertib. part 2. Total synthesis and first kilogram scale-up

Remarchuk, Travis,St-Jean, Frederic,Carrera, Diane,Savage, Scott,Yajima, Herbert,Wong, Brian,Babu, Srinivasan,Deese, Alan,Stults, Jeffrey,Dong, Michael W.,Askin, David,Lane, Jonathan W.,Spencer, Keith L.

, p. 1652 - 1666 (2015/02/19)

Herein, the first-generation process to manufacture Akt inhibitor Ipatasertib through a late-stage convergent coupling of two challenging chiral components on multikilogram scale is described. The first of the two key components is a trans-substituted cyc

PROCESS FOR MAKING AMINO ACID COMPOUNDS

-

, (2013/12/03)

The invention provides new processes for making and purifying amino acid compounds, which are useful in the preparation of AKT inhibitors used in the treatment of diseases such as cancer, including the compound (S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one.

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