154498-13-2Relevant articles and documents
COMPOUNDS AND METHODS
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, (2013/03/26)
The present invention relates to novel retinoid-related orphan receptor gamma (RORy) modulators and their use in the treatment of diseases mediated by RORy.
Conformationally constrained [p-(ω-aminoalkyl)phenacetyl]-L-seryl-L- lysyl dipeptide amides as potent peptidomimetic inhibitors of Candida albicans and human myristoyl-CoA:protein N-myristoyl transferase
Nagarajan, Srinivasan R.,Devadas, Balekudru,Zupec, Mark E.,Freeman, Sandra K.,Brown, David L.,Lu, Hwang-Fun,Mehta, Pramod P.,Kishore, Nandini S.,McWherter, Charles A.,Getman, Daniel P.,Gordon, Jeffrey I.,Sikorski, James A.
, p. 1422 - 1438 (2007/10/03)
MyristoylCoA:protein N-myristoyltransferase (NMT) covalently attaches the 14-carbon saturated fatty acid myristate, via an amide bond, to the N- terminal glycine residues of a variety of cellular proteins. Genetic studies have shown that NMT is essential
PYRIDINE COMPOUNDS WHICH ARE USEFUL AS LEUKOTRIENE-B4-ANTAGONISTS
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, (2008/06/13)
The invention relates to new pyridine derivatives of general formula I which have useful properties, e.g., as leukotriene-B 4-antagonists. Pharmaceutical compositions containing these compounds can be used to treat various diseases.