1620749-79-2 Usage
Uses
Used in Pharmaceutical Industry:
3-bromo-2-(trifluoromethyl)quinoline is used as a building block for the synthesis of various pharmaceuticals. Its unique structure allows for the creation of new compounds with potential therapeutic properties. The trifluoromethyl group enhances the compound's lipophilicity, potentially improving the bioavailability and pharmacokinetics of the resulting drugs.
Used in Agrochemical Industry:
In the agrochemical industry, 3-bromo-2-(trifluoromethyl)quinoline serves as a key intermediate for the development of new pesticides and herbicides. Its chemical properties enable the design of novel compounds with improved efficacy and selectivity, contributing to more effective and environmentally friendly agricultural practices.
Used in Organic Synthesis:
3-bromo-2-(trifluoromethyl)quinoline is utilized as a versatile intermediate in organic synthesis. Its reactivity and functional groups make it suitable for various chemical reactions, allowing the formation of a wide range of compounds with diverse applications in research and industry.
Used in Medicinal Chemistry Research:
3-bromo-2-(trifluoromethyl)quinoline is employed in medicinal chemistry research to explore its pharmacological properties. Its unique structure and potential biological activities make it an interesting candidate for the development of new drugs and therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 1620749-79-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,2,0,7,4 and 9 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1620749-79:
(9*1)+(8*6)+(7*2)+(6*0)+(5*7)+(4*4)+(3*9)+(2*7)+(1*9)=172
172 % 10 = 2
So 1620749-79-2 is a valid CAS Registry Number.
1620749-79-2Relevant articles and documents
Stable but reactive perfluoroalkylzinc reagents: Application in ligand-free copper-catalyzed perfluoroalkylation of aryl iodides
Aikawa, Kohsuke,Nakamura, Yuzo,Yokota, Yuki,Toya, Wataru,Mikami, Koichi
supporting information, p. 96 - 100 (2015/02/05)
The aromatic perfluoroalkylation catalyzed by a copper(I) salt with bis(perfluoroalkyl)zinc reagents Zn(RF)2(DMPU)2, which were prepared and then isolated as a stable white powder from perfluoroalkyl iodide and diethylzinc, was accomplished to provide the perfluoroalkylated products in good-to-excellent yields. The advantages of this reliable and practical catalytic reaction are 1) airstable and easy-to-handle bis(perfluoroalkyl)zinc reagents can be utilized, 2) the reagent is reactive and hence the operation without activators and ligands is simple, and 3) not only trifluoromethylation but also perfluoroalkylation can be attained.
Efficient copper-catalyzed trifluoromethylation of aromatic and heteroaromatic iodides: The beneficial anchoring effect of borates
Gonda, Zsombor,Kovacs, Szabolcs,Weber, Csaba,Gati, Tamas,Meszaros, Attila,Kotschy, Andras,Novak, Zoltan
supporting information, p. 4268 - 4271 (2014/09/30)
Efficient copper-catalyzed trifluoromethylation of aromatic iodides was achieved with TMSCF3 in the presence of trimethylborate. The Lewis acid was used to anchor the in situ generated trifluoromethyl anion and suppress its rapid decomposition. Broad applicability of the new trifluoromethylating reaction was demonstrated in the functionalization of different aromatic and heteroaromatic iodides.
