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2-Methoxy-4,6-di(trifluoromethyl)benzoic acid is a chemical compound characterized by the molecular formula C10H7F6O3. It is a benzoic acid derivative featuring a methoxy group and two trifluoromethyl groups attached to the benzene ring. The unique chemical properties conferred by these functional groups make it a versatile building block in various industrial applications.

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  • 180134-15-0 Structure
  • Basic information

    1. Product Name: 2-METHOXY-4,6-DI(TRIFLUOROMETHYL)BENZOIC ACID
    2. Synonyms: 2-Methoxy-4,6-bis(trifluoromethyl)benzoic acid;6-Methoxy-2,4-bis(trifluoroMethyl)benzoic acid, 97%
    3. CAS NO:180134-15-0
    4. Molecular Formula: C10H6F6O3
    5. Molecular Weight: 288.142
    6. EINECS: N/A
    7. Product Categories: Benzene series;Carboxylic Acids;Phenyls & Phenyl-Het;Carboxylic Acids;Phenyls & Phenyl-Het
    8. Mol File: 180134-15-0.mol
  • Chemical Properties

    1. Melting Point: 156-159℃
    2. Boiling Point: 253.641 °C at 760 mmHg
    3. Flash Point: 107.199 °C
    4. Appearance: /
    5. Density: 1.493 g/cm3
    6. Vapor Pressure: 0.009mmHg at 25°C
    7. Refractive Index: 1.43
    8. Storage Temp.: Sealed in dry,Room Temperature
    9. Solubility: N/A
    10. CAS DataBase Reference: 2-METHOXY-4,6-DI(TRIFLUOROMETHYL)BENZOIC ACID(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-METHOXY-4,6-DI(TRIFLUOROMETHYL)BENZOIC ACID(180134-15-0)
    12. EPA Substance Registry System: 2-METHOXY-4,6-DI(TRIFLUOROMETHYL)BENZOIC ACID(180134-15-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 180134-15-0(Hazardous Substances Data)

180134-15-0 Usage

Uses

Used in Pharmaceutical Synthesis:
2-Methoxy-4,6-di(trifluoromethyl)benzoic acid is utilized as a key intermediate in the synthesis of pharmaceuticals. Its unique structure allows for the development of new drugs with enhanced properties, such as improved potency, selectivity, and bioavailability.
Used in Agrochemical Production:
In the agrochemical industry, 2-Methoxy-4,6-di(trifluoromethyl)benzoic acid serves as an essential component in the production of various agrochemicals. Its incorporation into these compounds can lead to more effective and targeted pest control solutions.
Used in Organic Synthesis as a Building Block:
2-Methoxy-4,6-di(trifluoromethyl)benzoic acid is employed as a building block in organic synthesis, enabling the creation of a wide range of organic compounds with diverse applications. Its unique functional groups facilitate various chemical reactions, expanding the scope of synthetic chemistry.
Used in Dye and Pigment Production:
As an intermediate in the production of dyes and pigments, 2-Methoxy-4,6-di(trifluoromethyl)benzoic acid contributes to the development of novel colorants with improved properties, such as increased stability, brightness, and colorfastness. Its presence in these compounds can lead to innovative applications in various industries, including textiles, plastics, and printing inks.

Check Digit Verification of cas no

The CAS Registry Mumber 180134-15-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,0,1,3 and 4 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 180134-15:
(8*1)+(7*8)+(6*0)+(5*1)+(4*3)+(3*4)+(2*1)+(1*5)=100
100 % 10 = 0
So 180134-15-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H6F6O3/c1-19-6-3-4(9(11,12)13)2-5(10(14,15)16)7(6)8(17)18/h2-3H,1H3,(H,17,18)

180134-15-0 Well-known Company Product Price

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  • (Code)Product description
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  • Alfa Aesar

  • (H26448)  6-Methoxy-2,4-bis(trifluoromethyl)benzoic acid, 97%   

  • 180134-15-0

  • 1g

  • 621.0CNY

  • Detail
  • Alfa Aesar

  • (H26448)  6-Methoxy-2,4-bis(trifluoromethyl)benzoic acid, 97%   

  • 180134-15-0

  • 5g

  • 2060.0CNY

  • Detail

180134-15-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-methoxy-4,6-bis(trifluoromethyl)benzoic acid

1.2 Other means of identification

Product number -
Other names 6-Methoxy-2,4-bis(trifluoromethyl)benzoic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:180134-15-0 SDS

180134-15-0Relevant articles and documents

2-Methoxy-4,6-bis(trifluoromethyl)phenyllithium: A new stable aryllithium useful as an intermediate to bis(trifluoromethyl)aromatics

Dmowski, Wojciech,Piasecka-Maciejewska, Krystyna

, p. 59 - 63 (2007/10/03)

A method for the preparation of 3,5-bis(trifluoromethyl)anisole (3) has been developed. Lithiation of 3 occurred exclusively at the position ortho to the CH3O group to give a thermally stable lithium derivative 6 which readily undergoes conventional reactions with a number of electrophiles. Formylation and carboxylation of 6 gave bis(trifluoromethyl) derivatives of salicylic aldehyde and salicylic acid 9-12 in good yields.

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