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CAS

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468-10-0

Morphinan is a class of organic compounds that are derived from the opium poppy plant, Papaver somniferum. It is the parent compound of a variety of opioids, including morphine, codeine, and heroin. Morphinan compounds are known for their potent analgesic properties and are widely used in the medical field for pain management. However, their use is strictly regulated due to their potential for addiction and abuse. The structure of morphinan compounds allows them to interact with opioid receptors in the brain, which can lead to feelings of euphoria and pain relief. Despite their therapeutic benefits, the misuse of morphinan-based drugs is a significant public health concern.

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  • 468-10-0 Structure

  • Basic information

    1. Product Name: Morphinan
    2. Synonyms: Morphinan
    3. CAS NO:468-10-0
    4. Molecular Formula: C16H21N
    5. Molecular Weight: 227.3446
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 468-10-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: bp0.05 115°
    3. Flash Point: 183°C
    4. Appearance: /
    5. Density: 1.09g/cm3
    6. Refractive Index: 1.598
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Morphinan(CAS DataBase Reference)
    10. NIST Chemistry Reference: Morphinan(468-10-0)
    11. EPA Substance Registry System: Morphinan(468-10-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 468-10-0(Hazardous Substances Data)

468-10-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 468-10-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,6 and 8 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 468-10:
(5*4)+(4*6)+(3*8)+(2*1)+(1*0)=70
70 % 10 = 0
So 468-10-0 is a valid CAS Registry Number.
InChI:InChI=1/C16H21N/c1-2-6-13-12(5-1)11-15-14-7-3-4-8-16(13,14)9-10-17-15/h1-2,5-6,14-15,17H,3-4,7-11H2/t14-,15+,16-/m0/s1

468-10-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene

1.2 Other means of identification

Product number -
Other names Morphinan

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:468-10-0 SDS

468-10-0Relevant articles and documents

Morphinan derivatives and pharmaceutical use thereof

-

, (2008/06/13)

A morphinan derivative or its pharmaceutically acceptable acid addition salt represented with, for example, and an analgesic, diuretic, antitussive and brain cell protector having its derivative or its salt as the active ingredient are described. The compound of the present invention possesses strong analgesic activity, diuretic action and antitussive action as a highly selective κ-opioid agonist, allowing it to be used as a useful analgesic, diuretic and antitussive. On the other hand, the compound of the present invention also possesses remarkable cerebro-neuroprotective activity, thus allowing it be used as a useful cerebro-neuroprotective agents.

Process for preparing a morphinan derivative

-

, (2008/06/13)

A process for preparing a morphinan derivative by providing a dihydrofuranyl bridged tetracycle halide of the formula (19) STR1 in which X is halogen, R is an alkyl group of from 1 to about 10 carbon atoms, and R1 is a protecting group. The pentacycle halide is converted into a morphinan derivative of formula (20) STR2 in which R is a previously defined.

Short total synthesis or morphinan compounds which uses cyclization of a cycloalkylcarbonyl compound selected from cyclopropylcarbonyl and cyclobutylcarbonyl

-

, (2008/06/13)

There is disclosed herewith a method of producing morphinan compounds by total synthesis which incorporates utilization of N-cycloalkylcarbonyl compounds, which show certain advantages over the prior art which has been previously expressed in U.S. Pat. No. 4,368,326.

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