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(1S,3S)-3-Aminocyclopentanol, also known as 3-amino-1-cyclopentanol, is a chiral chemical compound with the molecular formula C5H11NO. It features a cyclic amine alcohol structure and possesses two stereocenters, existing in two enantiomeric forms, (1S,3S) and (1R,3R). (1S,3S)-3-Aminocyclopentanol is significant in organic synthesis and pharmaceutical manufacturing due to its unique structural and stereochemical properties, making it a valuable intermediate for the synthesis of chiral molecules and pharmaceuticals.

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  • 946593-67-5 Structure
  • Basic information

    1. Product Name: (1S,3S)-3-Aminocyclopentanol
    2. Synonyms: (1S,3S)-3-aMinocyclopentan-1-ol;(1S,3S)-1-Amino-3-hydroxycyclopentane;(1S,3S)-3-AMINOCYCLOPENTA;Trans-3-AMinocyclopentanol (HCl ForM);(1S,3S)-3-Aminocyclopentanol;Cyclopentanol, 3-aMino-, (1S,3S)-;(1S,3S)-3-Aminocyclopentanol(WX600233)
    3. CAS NO:946593-67-5
    4. Molecular Formula: C5H11NO
    5. Molecular Weight: 101
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 946593-67-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 179℃
    3. Flash Point: 62℃
    4. Appearance: /
    5. Density: 1.084
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C(protect from light)
    8. Solubility: N/A
    9. PKA: 15.06±0.40(Predicted)
    10. CAS DataBase Reference: (1S,3S)-3-Aminocyclopentanol(CAS DataBase Reference)
    11. NIST Chemistry Reference: (1S,3S)-3-Aminocyclopentanol(946593-67-5)
    12. EPA Substance Registry System: (1S,3S)-3-Aminocyclopentanol(946593-67-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 946593-67-5(Hazardous Substances Data)

946593-67-5 Usage

Uses

Used in Organic Synthesis:
(1S,3S)-3-Aminocyclopentanol is used as a building block in organic synthesis for its ability to contribute to the formation of complex molecular structures. Its chiral nature allows for the creation of enantioselective compounds, which is crucial in producing specific biologically active molecules.
Used in Pharmaceutical Manufacturing:
In the pharmaceutical industry, (1S,3S)-3-Aminocyclopentanol serves as an important intermediate. Its incorporation into the synthesis of various drugs leverages its chiral properties to achieve desired pharmacological effects, ensuring the production of enantiomerically pure compounds for targeted therapeutic applications.
Used in Drug Development:
(1S,3S)-3-Aminocyclopentanol is utilized in the development of new drugs and biologically active compounds. Its unique stereochemistry plays a role in the discovery and design of novel therapeutic agents, potentially leading to advancements in medicinal chemistry and the treatment of various diseases.
Each application highlights the versatility and importance of (1S,3S)-3-Aminocyclopentanol in different sectors, emphasizing its role as a key component in the creation and enhancement of pharmaceuticals and organic compounds.

Check Digit Verification of cas no

The CAS Registry Mumber 946593-67-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,6,5,9 and 3 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 946593-67:
(8*9)+(7*4)+(6*6)+(5*5)+(4*9)+(3*3)+(2*6)+(1*7)=225
225 % 10 = 5
So 946593-67-5 is a valid CAS Registry Number.

946593-67-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name (1S,3S)-3-aminocyclopentan-1-ol

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:946593-67-5 SDS

946593-67-5Relevant articles and documents

4-CYCLOALKYLAMINOPYRAZOLO PYRIMIDINE NMDA/NR2B ANTAGONISTS

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Page/Page column 49, (2010/02/11)

Compounds represented by Formula (I): or pharmaceutically acceptable salts thereof, are effective as NMDA/NR2B antagonists useful for treating neurological conditions such as, for example, pain, Parkinson's disease, Alzheimer's disease, epilepsy, depression, anxiety, ischemic brain injury including stroke, and other conditions.

2-Substituted-1H-benz(de)-isoquinoline-1,3-(2H)-diones

-

, (2008/06/13)

Compounds of the following formula STR1 wherein R1 and R2 are independently selected from hydrogen, halogen, lower alkyl, lower alkoxy, lower alkylthio, nitro, cyano, and trifluoromethyl, and R is selected from a triacetyl substituted pentose, pentose, a tetraacetyl substituted hexose, hexose, a hydroxy substituted cycloalkyl of 5 to 7 carbons, STR2 wherein n is 1 or 2 and R3 is hydrogen, an alkali metal or alkaline earth metal ion; are disclosed. These compounds possess useful anti-inflammatory activity.

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