5,5-Dimethylhydantoin (77-71-4) 's Synthetic route

A safe production method for acetone cyanohydrin

Heugebaert, Thomas S.A.  Roman, Bart I.  De Blieck, Ann  Stevens, Christian V.

An easily amenable method is presented to produce acetone cyanohydrin on mole scale (output 39 g/h), using a continuous flow system to overcome the high risks associated with the large-scale use of hydrogen cyanide.