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Name |
α-Chloroacetoacetic acid monoethyl-amide |
EINECS | N/A |
CAS No. | 4116-10-3 | Density | 1.188g/cm3 |
PSA | 46.17000 | LogP | 0.31970 |
Solubility | N/A | Melting Point |
78-80 °C |
Formula | C5H8 Cl N O2 | Boiling Point | 284.1°Cat760mmHg |
Molecular Weight | 149.577 | Flash Point | 125.6°C |
Transport Information | N/A | Appearance | N/A |
Safety | Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NOx and Cl−. | Risk Codes | 22-24-37/38-41-43 |
Molecular Structure | Hazard Symbols | ||
Synonyms |
Acetoacetamide,2-chloro-N-methyl- (7CI,8CI); 2-Chloro-N-methyl-3-oxobutanamide;2-Chloro-N-methylacetoacetamide; N-Methyl-2-chloroacetoacetamide |
Article Data | 3 |
IUPAC Name: 2-Chloro-N-methyl-3-oxobutanamide
Synonyms of α-Chloroacetoacetic acid monoethyl-amide (CAS NO.4116-10-3): 2-Chloro-N-methyl-3-oxobutanamide ; 2-Chloro-N-methylacetoacetamide ; N-Methyl-2 chloroacetoacetamide ; alpha-Chloracetessigsaeureaethylamid ; alpha-Chloroacetoacetic acid monoethylamide ; Acetoacetamide, 2-chloro-N-ethyl- ; Butanamide, 2-chloro-N-methyl-3-oxo-
CAS NO: 4116-10-3
Molecular Formula: C5H8ClNO2
Molecular Weight : 149.5755
Molecular Structure:
EINECS: 223-907-5
H bond acceptors: 3
H bond donors: 1
Freely Rotating Bonds: 2
Polar Surface Area: 37.38 Å2
Index of Refraction: 1.447
Molar Refractivity: 33.67 cm3
Molar Volume: 125.8 cm3
Surface Tension: 34.4 dyne/cm
Density: 1.188 g/cm3
Flash Point: 125.6 °C
Enthalpy of Vaporization: 52.31 kJ/mol
Boiling Point: 284.1 °C at 760 mmHg
Vapour Pressure: 0.00304 mmHg at 25°C
Melting Point: 78-80°C
α-Chloroacetoacetic acid monoethyl-amide (CAS NO.4116-10-3) is a dedicated intermediates of pesticide monocrotophos .
Add Acetoacetyl methylamine aqueous solution in enamel reactor , then add salt and urea plus a small amount of Dichloroethane, set it cooled to -15 °C with stirring, and then slowly pass chlorine gas into the reactor, After passing a certain amount of chlorine gas, sample analysis, then aspirated into extraction kettle, heated to 40°C, with Dichloroethane extraction, concentrated extract drawn into the reactor, steamed out of Dichloroethane under normal pressure, that is α-Chloro-acetyl-acetyl-methylamine , directly put it into the synthesis reactor for the next step reaction.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | oral | 750mg/kg (750mg/kg) | BEHAVIORAL: ANTIPSYCHOTIC LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Archiv fuer Toxikologie. Vol. 18, Pg. 316, 1960. |
rat | LD50 | oral | 700mg/kg (700mg/kg) | BEHAVIORAL: ANTIPSYCHOTIC LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Archiv fuer Toxikologie. Vol. 18, Pg. 316, 1960. |
Reported in EPA TSCA Inventory.
Hazard Codes: T
Risk Statements: 22-24-37/38-41-43
R22 :Harmful if swallowed.
R24: α-Chloroacetoacetic acid monoethyl-amide (CAS NO.4116-10-3) is toxic in contact with skin.
R37/38: Irritating to respiratory system and skin.
R41: Risk of serious damage to the eyes.
R43: May cause sensitization by skin contact.
Safety Statements: 26-28-36/37/39-45
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S28: After contact with skin, wash immediately with plenty of soap-suds.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: 2923
RTECS: AK3910000
HazardClass: 8
PackingGroup: III
Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NOx and Cl−.