Basic information
- Name:
Pyridine, 2,6-dimethyl-
- Superlist Name:
- 2,6-Lutidine
- CAS No.:
108-48-5
- Molecular Structure:
- Formula:
- C7H9N
- Molecular Weight:
- 107.17
- Synonyms:
- a,a'-Lutidine;2,6-Dimethylpyridine;NSC 2155;a,a'-Dimethylpyridine;2,6-Lutidine(8CI);
- EINECS:
- 203-587-3
- Density:
- 0.9252 g/cm3
- Melting Point:
- -6 °C
- Boiling Point:
- 144 °C at 760 mmHg
- Flash Point:
- 33.3 °C
- Solubility:
- 40 g/100 mL (20 °C) in water
- Appearance:
- Colorless to yellow liquid
- Hazard Symbols:
Xn- Risk Codes:
- 10-22-36/37/38-20/21/22
- Safety Description:
- 26-36/37-16-36-36/37/39 Details
- Transport Information:
- UN 1993 3/PG 3
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Chemistry
Molecular Formula: C7H9N 
Formula Weight: 107.15
mp of 2,6-LUTIDINE (108-48-5): -6 °C
bp : 143-145 °C(lit.)
density : 0.92 g/mL at 25 °C(lit.)
refractive index : n20/D 1.497(lit.)
Fp of 2,6-LUTIDINE (108-48-5): 92 °F
storage temp. : -20°C
Water Solubility : 40 g/100 mL (20 oC)
Odor: Characteristic.
Color: Straw color.
Solubility: Easily soluble in cold water.
2,6-LUTIDINE (108-48-5) is a colorless to yellow oily liquid.
Formula Weight: 107.15
mp of 2,6-LUTIDINE (108-48-5): -6 °C
bp : 143-145 °C(lit.)
density : 0.92 g/mL at 25 °C(lit.)
refractive index : n20/D 1.497(lit.)
Fp of 2,6-LUTIDINE (108-48-5): 92 °F
storage temp. : -20°C
Water Solubility : 40 g/100 mL (20 oC)
Odor: Characteristic.
Color: Straw color.
Solubility: Easily soluble in cold water.
2,6-LUTIDINE (108-48-5) is a colorless to yellow oily liquid.
Uses
In organic synthesis, 2,6-LUTIDINE (108-48-5) is widely used as a sterically hindered mild base. It is also used as a vulcanization accelerator for pesticides, dyes, dyes, resins and rubber. And also can be used as a solvent.
Production
Recycling β-methylpyridine fractions from coal by-products of coking, then separating β-methylpyridine fractions, we can obtain 2,6-LUTIDINE (108-48-5).
Toxicity Data With Reference
| 1. | sln-smc 5000 ppm | MUREAV Mutation Research. 163 (1986),23. | ||
| 2. | orl-rat LD50:400 mg/kg | 85JCAE Prehled Prumyslove Toxikologie; Organicke Latky Marhold, J.,Prague, Czechoslovakia.: Avicenum,1986,845. | ||
| 3. | ihl-rat LCLo:7500 ppm/1H | 85JCAE Prehled Prumyslove Toxikologie; Organicke Latky Marhold, J.,Prague, Czechoslovakia.: Avicenum,1986,845. | ||
| 4. | skn-gpg LD50:2500 mg/kg | 85JCAE Prehled Prumyslove Toxikologie; Organicke Latky Marhold, J.,Prague, Czechoslovakia.: Avicenum,1986,845. |
Consensus Reports
Reported in EPA TSCA Inventory.
Safety Profile
Hazard Codes : Xn,F,Xi (Harmful; Highly Flammable; Irritant)
Risk Statements : 10-22-36/37/38-20/21/22 (Flammable; Harmful if swallowed; Irritating to eyes, respiratory system and skin; Harmful by inhalation, in contact with skin and if swallowed)
Safety Statements : 26-36/37-16-36-36/37/39 (In case of contact with eyes, rinse immediately with plenty of water and seek medical advice; Wear suitable protective clothing and gloves; Keep away from sources of ignition - No smoking; Wear suitable protective clothing; Wear suitable protective clothing, gloves and eye/face protection)
RIDADR : UN 1993 3/PG 3
WGK Germany : 3
RTECS : OK9700000
F : 8 (Photosensitive)
Hazard Note : Irritant/Flammable
HazardClass : 3
PackingGroup : III
HS Code : 29333999
Poison by ingestion. Moderately toxic by skin contact. Mildly toxic by inhalation. Mutation data reported. When heated to decomposition it emits toxic vapors of NOx.
Risk Statements : 10-22-36/37/38-20/21/22 (Flammable; Harmful if swallowed; Irritating to eyes, respiratory system and skin; Harmful by inhalation, in contact with skin and if swallowed)
Safety Statements : 26-36/37-16-36-36/37/39 (In case of contact with eyes, rinse immediately with plenty of water and seek medical advice; Wear suitable protective clothing and gloves; Keep away from sources of ignition - No smoking; Wear suitable protective clothing; Wear suitable protective clothing, gloves and eye/face protection)
RIDADR : UN 1993 3/PG 3
WGK Germany : 3
RTECS : OK9700000
F : 8 (Photosensitive)
Hazard Note : Irritant/Flammable
HazardClass : 3
PackingGroup : III
HS Code : 29333999
Poison by ingestion. Moderately toxic by skin contact. Mildly toxic by inhalation. Mutation data reported. When heated to decomposition it emits toxic vapors of NOx.
Specification
Storage: Keep container tightly closed. Keep in a cool, well-ventilated place. Keep away from heat. Keep
away from sources of ignition. A refrigerated room would be preferable for materials with a flash point lower than
37.8°C (100°F). Flammable materials should be stored in a separate safety storage cabinet or room. Ground all
equipment containing material.
away from sources of ignition. A refrigerated room would be preferable for materials with a flash point lower than
37.8°C (100°F). Flammable materials should be stored in a separate safety storage cabinet or room. Ground all
equipment containing material.
