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Basic information

  • Name:
  • Arteether

  • CAS No.:
  • 75887-54-6

  • Molecular Structure:
  • Formula:
  • C17H28O5
  • Molecular Weight:
  • 312.40
  • Deleted CAS:
  • 159510-58-4
  • Synonyms:
  • 3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin,10-ethoxydecahydro-3,6,9-trimethyl-, [3R-(3a,5ab,6b,8ab,9a,10a,12b,12aR*)]-;Artemotil;Dihydroqinghaosu ethyl ether;NSC 665971;SM 227;b-Arteether;3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin,10-ethoxydecahydro-3,6,9-trimethyl-, (3R,5aS,6R,8aS,9R,10S,12R,12aR)-;
  • Density:
  • 1.16 g/cm3
  • Melting Point:
  • 80-820 °C
  • Boiling Point:
  • 372.4 °C at 760 mmHg
  • Flash Point:
  • 146 °C
  • Appearance:
  • white crystalline solid

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Chemistry

Molecular structure of Arteether (CAS NO.75887-54-6) is:

Product Name: Arteether
CAS Registry Number: 75887-54-6
Molecular Weight: 312.40122 [g/mol]
Molecular Formula: C17H28O5
XLogP3-AA: 3.4
H-Bond Donor: 0
H-Bond Acceptor: 5
Melting Point: 80-820  °C
Surface Tension: 39.7 dyne/cm
Density: 1.16 g/cm3
Flash Point: 146 °C
Enthalpy of Vaporization: 59.52 kJ/mol
Boiling Point: 372.4 °C at 760 mmHg
Vapour Pressure: 2.06E-05 mmHg at 25°C 
Product Categories: Antimalarial;Intermediates & Fine Chemicals;Pharmaceuticals

Uses

 Arteether (CAS NO.75887-54-6) is a fast acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria cases.

Specification

 Arteether , its cas register number is 75887-54-6. It also can be called (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-Ethoxydecahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin ; Artemotil ; Dihydroartemisinin ethyl ether ; 3,12-Epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin, 10-ethoxydecahydro-3,6,9-trimethyl-, (3S-(3alpha,5alpha,6alpha,8aalpha,9beta,10beta,12beta,12aalpha))- ; 3,12-Epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin, decahydro-10-ethoxy-3,6,9-trimethyl-, (3R-(3alpha,5abeta,6beta,8abeta,9alpha,10alpha,12beta,12aR*))- . It is a white crystalline solid.

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