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Cas Database |
| Name |
D-Lysine, hydrochloride (1:1) |
EINECS | 230-691-6 |
| CAS No. | 7274-88-6 | Density | N/A |
| PSA | 89.34000 | LogP | 1.72990 |
| Solubility | Soluble in water | Melting Point |
266 °C (dec.)(lit.) |
| Formula | C6H15ClN2O2 | Boiling Point | 311.5 °C at 760 mmHg |
| Molecular Weight | 182.65 | Flash Point | 142.2 °C |
| Transport Information | N/A | Appearance | white crystalline powder |
| Safety | 24/25 | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
D-Lysine,monohydrochloride (9CI);Lysine, monohydrochloride, D- (8CI);NSC 206291;H-D-Lys-OH.HCl;H-D-Lys-OH·HCl; |
Article Data | 2 |
D-Lysine, hydrochloride (1:1) Synthetic route
| Conditions | Yield |
|---|---|
| With hydrogenchloride In methanol at 20℃; for 15h; Reflux; | 95% |
| Conditions | Yield |
|---|---|
| With sodium hydroxide In 1,4-dioxane | 64% |
- 1277191-84-0
2,5-dioxopyrrolidin-1-yl 6-(((tert-butyldimethylsilyl)oxy)methyl)nicotinate
- 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide
- 7274-88-6
D-lysine hydrochloride
- 1277191-85-1
(R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-6-(6-(((tert-butyldimethylsilyl)oxy)methyl)nicotinamido)hexanoic acid
| Conditions | Yield |
|---|---|
| Stage #1: D-lysine hydrochloride With copper(ll) sulfate pentahydrate; sodium hydrogencarbonate In water for 2h; Reflux; Stage #2: 2,5-dioxopyrrolidin-1-yl 6-(((tert-butyldimethylsilyl)oxy)methyl)nicotinate In N,N-dimethyl-formamide at 0 - 20℃; for 16h; Stage #3: N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide Further stages; | 62% |
- 14464-31-4
palmitic acid N-succinimide ester
- 7274-88-6
D-lysine hydrochloride
- 870789-29-0
Pam-DLys(Pam)-OH
| Conditions | Yield |
|---|---|
| Stage #1: palmitic acid N-succinimide ester; D-lysine hydrochloride With sodium carbonate In 1,4-dioxane at 20℃; for 48h; Stage #2: With hydrogenchloride In 1,4-dioxane; water | 61% |
| Conditions | Yield |
|---|---|
| With copper(ll) sulfate pentahydrate; sodium carbonate; sodium hydroxide In water at 0 - 20℃; for 4h; Inert atmosphere; | 45.3% |
- 7274-88-6
D-lysine hydrochloride
- 28957-33-7
(R)-3-amino-azepan-2-one
| Conditions | Yield |
|---|---|
| With hexamethyldisilazan In toluene for 168h; Heating / reflux; | 15% |
| Stage #1: D-lysine hydrochloride With thionyl chloride In methanol at -60 - 20℃; for 12h; Stage #2: With sodium methylate In methanol for 4h; Reflux; | |
| Multi-step reaction with 2 steps 1: hydrogenchloride / 3 h / Reflux 2: sodium methylate / methanol / 4 h / Reflux View Scheme |
- 18595-34-1
tert-butyl fluoroformate
- 7274-88-6
D-lysine hydrochloride
- 31202-69-4
Nε-(tert-butoxycarbonyl)-D-lysine
| Conditions | Yield |
|---|---|
| (i) CuCO3*Cu(OH)2, (ii) aq. NaOH, NaHCO3, dioxane; Multistep reaction; |
- 1538-75-6
2,2-dimethylpropanoic anhydride
- 57538-27-9
2-methyl-1-nitroisourea
- 7274-88-6
D-lysine hydrochloride
- 132718-70-8
Nα-tert-butoxycarbonyl-NG-nitro-D-homoarginine
| Conditions | Yield |
|---|---|
| Yield given. Multistep reaction; |
- 7274-88-6
D-lysine hydrochloride
- 501-53-1
benzyl chloroformate
- 34404-32-5, 1155-64-2, 32302-83-3
(R)-2-amino-6-(((benzyloxy)carbonyl)amino)hexanoic acid
| Conditions | Yield |
|---|---|
| With copper (II) carbonate hydroxide; sodium hydroxide 1.) H2O, reflux, 2.5 h, 2.) RT, overnight; Yield given. Multistep reaction; |
| Conditions | Yield |
|---|---|
| With TEA 1.) H2O, reflux, 30 min, 2.) H2O, MeOH, a) 0 deg C, 1.5 h, b) RT, 1 h; Yield given. Multistep reaction; |
D-Lysine, hydrochloride (1:1) Chemical Properties
Product Name: D-Lysine hydrochloride (CAS NO.7274-88-6)
Molecular Formula: C6H15ClN2O2
Molecular Weight: 182.648500 g/mol
Appearance: brown power
Melting Point: 266 °C (dec.)(lit.)
Solubility: soluble
Alpha: -21 °(c=8, 6N HCl)
Storage temp.: Store at RT.
BRN: 4356907
Flash Point: 142.2 °C
Enthalpy of Vaporization: 60.75 kJ/mol
Boiling Point: 311.5 °C at 760 mmHg
Vapour Pressure: 0.000123 mmHg at 25°C
H-Bond Donor: 4
H-Bond Acceptor: 4
Structure Descriptors of D-Lysine hydrochloride (CAS NO.7274-88-6):
IUPAC Name: 2,6-diaminohexanoic acid hydrochloride
Canonical SMILES: C(CCN)CC(C(=O)O)N.Cl
InChI: InChI=1S/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H
InChIKey: BVHLGVCQOALMSV-UHFFFAOYSA-N
Categories: Lysine [Lys, K]; Amino Acids and Derivatives; alpha-Amino Acids; Amino Acids; Biochemistry; Amino hydrochloride
D-Lysine, hydrochloride (1:1) Uses
D-Lysine hydrochloride (CAS NO.7274-88-6) is a kind of hormones which is used to adjust endocrine.
D-Lysine, hydrochloride (1:1) Toxicity Data With Reference
| 1. | ipr-rat LD50:4750 mg/kg ABBIA4 64,319,56 |
D-Lysine, hydrochloride (1:1) Consensus Reports
Reported in EPA TSCA Inventory.
D-Lysine, hydrochloride (1:1) Safety Profile
Safety Information of D-Lysine hydrochloride (CAS NO.7274-88-6):
Safety Statements:24/25
24/25:Avoid contact with skin and eyes
WGK Germany:3
RTECS:OL5632500
F:21
When heated to decomposition it emits very toxic fumes of HCl and NOx.
D-Lysine, hydrochloride (1:1) Specification
D-Lysine hydrochloride , its CAS NO. is 7274-88-6, the synonyms are D-Lysine, monohydrochloride ; Lysine, hydrochloride, D- ; Lysine, monohydrochloride, D- .
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