Reported in EPA TSCA Inventory.

ACGIH TLV: TWA 2 mg(Al)/m³

The Diisobutylaluminium hydride, with the CAS registry number 1191-15-7, is also known as Hydrobis(2-methylpropyl)aluminum. It belongs to the product categories of Organometallics; Al (Alminum) Compounds; Biochemistry; Classes of Metal Compounds; Reagents for Oligosaccharide Synthesis; Reduction; Synthetic Organic Chemistry; Typical Metal Compounds; Metal alkyl. Its EINECS number is 214-729-9. This chemical's molecular formula is C₈H₁₉Al and molecular weight is 142.22. What's more, its systematic name is hydrido[bis(2-methylpropyl)]aluminum. It should be sealed and stored at the temperature of 2 - 8 °C. Moreover, it should be protected from oxides, heat and fire. It is a prostaglandin reducing agent. It is mainly used as reducing agent and hydrogen aluminum agent in the fine chemicals. It is useful in organic synthesis for a variety of reductions, including converting esters and nitriles to aldehydes.

Preparation of Diisobutylaluminium hydride:
Diisobutylaluminium hydride can be prepared by by thermal decomposition in the reduced pressure and at the temperature of 120- 180 °C with triisobutyl aluminium as raw materials. The yield is up to 95%.

Uses of Diisobutylaluminium hydride:
It can be used to produce O²,O³;O⁵,O⁶-diisopropyliden-1,4-anhydro-D-mannitol at the temperature of 0 °C. It will need solvent toluene with the reaction time of 10 min. The yield is about 71%.


When you are using Diisobutylaluminium hydride, please be cautious about it as the following:
Diisobutylaluminium hydride is harmful by inhalation, in contact with skin and if swallowed. If swallowed, it will not induce vomiting that you need seek medical advice immediately and show this container or label. It is harmful as it may cause lung damage if swallowed and has a danger of serious damage to health by prolonged exposure through inhalation. This chemical is toxic by inhalation, in contact with skin and if swallowed. Moreover, it is toxic to aquatic organisms as it may cause long-term adverse effects in the aquatic environment. The substance will react violently with water, liberating extremely flammable gases. Its vapours may cause drowsiness and dizziness. This chemical is spontaneously flammable in air and may form explosive peroxides. It can cause severe burns. It has a limited evidence of a carcinogenic effect and has a possible risk of harm to the unborn child and a possible risk of impaired fertility. This chemical is highly flammable, so you should keep it away from sources of ignition - No smoking. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. When using it, you need wear suitable protective clothing, gloves and eye/face protection. You must take off immediately all contaminated clothing. You should not empty it into drains. In case of accident or if you feel unwell, you must seek medical advice immediately (show the label where possible). You should avoid releasing it to the environment just refering to special instructions/safety data sheet.

You can still convert the following datas into molecular structure:
(1)SMILES: CC(C)C[AlH]CC(C)C
(2)Std. InChI:InChI=1S/2C4H9.Al.H/c2*1-4(2)3;;/h2*4H,1H2,2-3H3;
(3)Std. InChIKey: AZWXAPCAJCYGIA-UHFFFAOYSA-N

The toxicity data of Diisobutylaluminium hydride is as follows: