Fosinopril

The IUPAC name of Fosinopril is (2S,4S)-4-cyclohexyl-1-[2-[(2-methyl-1-propanoyloxypropoxy)-(4-phenylbutyl)phosphoryl]acetyl]pyrrolidine-2-carboxylic acid. With the CAS registry number 98048-97-6, it is also named as L-Proline, 4-cyclohexyl-1-(((2-methyl-1-(1-oxopropoxy)propoxy)(4-phenylbutyl)phosphinyl)acetyl)-, (2alpha,4beta)-. The classification codes are Angiotensin-converting enzyme inhibitors; Antihypertensive agents; Cardiovascular Agents; Enzyme Inhibitors; Protease Inhibitors. It is a prodrug that is converted to its active metabolite fosinoprilat. 

The other characteristics of this product can be summarized as: (1)ACD/LogP: 6.09; (2)# of Rule of 5 Violations: 2; (3)ACD/LogD (pH 5.5): 4.21; (4)ACD/LogD (pH 7.4): 2.63; (5)#H bond acceptors: 8; (6)#H bond donors: 1; (7)#Freely Rotating Bonds: 15; (8)Index of Refraction: 1.531; (9)Molar Refractivity: 148.8 cm³; (10)Molar Volume: 480.4 cm³; (11)Polarizability: 58.98×10^-24 cm³; (12)Surface Tension: 48.3 dyne/cm ; (13)Flash Point: 380.6 °C; (14)Enthalpy of Vaporization: 108.41 kJ/mol; (15)Boiling Point: 705.7 °C at 760 mmHg; (16)Vapour Pressure: 6.67E-21 mmHg at 25°C; (17)Rotatable Bond Count: 15; (18)Exact Mass: 563.301189; (19)MonoIsotopic Mass: 563.301189; (20)Topological Polar Surface Area: 110; (21)Heavy Atom Count: 39; (22)Complexity: 850; (23)Defined Atom StereoCenter Count: 2; (24)Undefined Atom StereoCenter Count: 2.

Uses of Fosinopril: It is an angiotensin converting enzyme (ACE) inhibitor used for the treatment of hypertension and some types of chronic heart failure.

People can use the following data to convert to the molecule structure. 
1. SMILES:O=C(CP(=O)(CCCCc1ccccc1)O[C@@H](OC(=O)CC)C(C)C)N2C[C@@H](C[C@H]2C(O)=O)C3CCCCC3
2. InChI:InChI=1/C30H46NO7P/c1-4-28(33)37-30(22(2)3)38-39(36,18-12-11-15-23-13-7-5-8-14-23)21-27(32)31-20-25(19-26(31)29(34)35)24-16-9-6-10-17-24/h5,7-8,13-14,22,24-26,30H,4,6,9-12,15-21H2,1-3H3,(H,34,35)/t25-,26+,30-,39-/m1/s1 
3. InChIKey:BIDNLKIUORFRQP-YPEQAXFABT