Hydroxychloroquine sulfate (747-36-4),Hydroxychloroquine sulfate (747-36-4) Manufacturers & Suppliers,Synthesis,MSDS

Basic information

Name:
Hydroxychloroquine sulfate
CAS No.:
747-36-4
Molecular Structure:
Formula:
C₁₈H₂₆ClN₃O^.H₂SO₄
Molecular Weight:
433.95
Synonyms:
Ethanol, 2-((4-((7-chloro-4-quinolyl)amino)pentyl)ethylamino)-, sulfate (1:1) (salt) (8CI);Plaquenil;Hydroxychloroquine sulfate (USP);Hidroxicloroquina [INN-Spanish];Ethanol, 2-((4-((7-chloro-4-quinolinyl)amino)pentyl)ethylamino)-, sulfate (1:1);Ercoquin;Ethanol, 2-[[4-[(7-chloro-4-quinolyl)amino]pentyl]ethylamino]-, monosulfate;Toremonil;2-((4-((7-Chloro-4-quinolinyl)amino)pentyl)ethylamino)ethanol sulfate (1:1) (salt);Idrossiclorochina [DCIT];Ethanol, 2-[[4-[ (7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-, sulfate (1:1) (salt);Ethanol,2-[[4-[(7-chloro-4-quinolinyl)amino]- pentyl]ethylamino]-,sulfate (1:1) (salt);Plaquinol;Hydroxychloroquinum [INN-Latin];Hydroxychloroquine sulphate;Plaquenil sulfate;Plaquenil (TN);HCQ;2-[4-[(7-chloroquinolin-4-yl)amino]pentyl-ethyl-amino]ethanol; sulfuric acid;Ethanol, 2-[[4-[ (7-chloro-4-quinolyl)amino]pentyl]ethylamino]-, sulfate (1:1) (salt);Hydroxy Chloroquine Sulphate;Hydroxychloroquine-Sulphate;
EINECS:
212-019-3
Melting Point:
240 °C
Boiling Point:
516.7 °C at 760 mmHg
Flash Point:
266.3 °C
Solubility:
Freely soluble in water
Appearance:
White cyrstalline solid
Hazard Symbols:
Xn, Xi
Risk Codes:
42/43-36/37/38-36-22
Safety Description:
37/39-26 Details

Famous Chemical Enterprises

Livzon
Total
Shell
Dupont
Exxonmobil
Akzonobel
Basf
Bayer
BP

Other Products

Please post your buying leads,so that our qualified suppliers will soon contact you!
*Required Fields

Chemistry

Molecular structure of Hydroxychloroquine sulfate (CAS NO.747-36-4) is:

Product Name: Hydroxychloroquine sulfate
CAS Registry Number: 747-36-4
IUPAC Name: 2-[4-[(7-chloroquinolin-4-yl)amino]pentyl-ethylamino]ethanol ; sulfuric acid
Molecular Weight: 433.95002 [g/mol]
Molecular Formula: C₁₈H₂₆ClN₃O^.H₂SO₄
H-Bond Donor: 4
H-Bond Acceptor: 8
EINECS: 212-019-3
Melting Point: 240 °C
Water Solubility: Freely Soluble
Flash Point: 266.3 °C
Enthalpy of Vaporization: 83.05 kJ/mol
Boiling Point: 516.7 °C at 760 mmHg
Vapour Pressure: 1.68E-11 mmHg at 25 °C
Product Categories: Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals

Uses

Hydroxychloroquine sulfate (CAS NO.747-36-4) can be used as an antimalarial, antirheumatic, lupus erythematosus suppressant.

Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
child	LDLo	oral	600mg/kg (600mg/kg)	BRAIN AND COVERINGS: OTHER DEGENERATIVE CHANGES CARDIAC: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA	Journal of Analytical Toxicology. Vol. 14, Pg. 186, 1990.
women	TDLo	oral	400mg/kg (400mg/kg)	CARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION	Journal of Toxicology, Clinical Toxicology. Vol. 37, Pg. 861, 1999.

Safety Profile

Safty information about Hydroxychloroquine sulfate (CAS NO.747-36-4) is:
Hazard Codes: Harmful Xn,Xi
Risk Statements: 42/43-36/37/38-36-22
R42/43:May cause sensitization by inhalation and skin contact.
R36/37/38:Irritating to eyes, respiratory system and skin.
R36:Irritating to eyes.
R22:Harmful if swallowed.
Safety Statements: 37/39-26
S37/39:Wear suitable gloves and eye/face protection.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
RTECS: KK3342500

Specification

Hydroxychloroquine sulfate , its cas register number is 747-36-4. It also can be called (+-)-2-((4-((7-Chloro-4-quinolyl)amino)pentyl)ethylamino)ethanol sulfate (1:1) (salt) ; 2-((4-((7-Chloro-4-quinolinyl)amino)pentyl)ethylamino)ethanol sulfate (1:1) (salt) ; 2-((4-((7-Chloro-4-quinolyl)amino)pentyl)ethylamino)ethanol sulfate (1:1) (salt) ; Ercoquin ; Ethanol, 2-((4-((7-chloro-4-quinolinyl)amino)pentyl)ethyl)amino-, (+-)-, sulfate (1:1) salt ; Ethanol, 2-((4-((7-chloro-4-quinolyl)amino)pentyl)ethylamino)-, sulfate (1:1) (salt) ; Plaquenil ; Plaquinol ; Toremonil .It is a odorless off-white solid.