Irinotecan (97682-44-5),Irinotecan (97682-44-5) Manufacturers & Suppliers,Synthesis,MSDS

Basic information

Name:
Irinotecan
CAS No.:
97682-44-5
Molecular Structure:
Formula:
C₃₃H₃₈N₄O₆
Molecular Weight:
586.69
Synonyms:
[1,4'-Bipiperidine]-1'-carboxylic acid,(4S)-4,11-diethyl-3,4,12,14-tetrahydro- 4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]- indolizino[1,2-b]quinolin-9-yl ester;(+)-Irinotecan;Irinotecan base;Irinotecanum [INN-Latin];Irrotecan hydrochloride;1,4'-bipiperidine-1'-carboxylic acid (s)-4,11-diethyl-3,4,12,14- tetrahydro-4-hydroxy-3,14-dioxo-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinolin -9-yl ester;Irinotecan HCL;Irinotecan(TECANS);
Density:
1.4 g/cm³
Boiling Point:
873.4 °C at 760 mmHg
Flash Point:
482 °C
Solubility:
soluble in water
Hazard Symbols:
Xn
Risk Codes:
22

Famous Chemical Enterprises

Livzon
Total
Shell
Dupont
Exxonmobil
Akzonobel
Basf
Bayer
BP

Other Products

Please post your buying leads,so that our qualified suppliers will soon contact you!
*Required Fields

Chemistry

Molecular formula: C₃₃H₃₈N₄O₆
Molecular Weight: 586.678g/mol
Structure of Irinotecan (CAS NO.97682-44-5):

Index of Refraction: 1.689
Molar Refractivity: 159.15 cm³
Molar Volume: 416.8 cm³
Polarizability: 63.09×10^-24cm³
Surface Tension: 74.2 dyne/cm
Density: 1.4 g/cm³
Flash Point: 482 °C
Enthalpy of Vaporization: 132.98 kJ/mol
Boiling Point: 873.4 °C at 760 mmHg
Vapour Pressure: 1.31E-32 mmHg at 25°C
Product Categories: Camptothecin series;APIs;Natural Anti-cancer Medical Materials and It's Derivatives;API's
Canonical SMILES: CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7
Isomeric SMILES: CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)[C@@]5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7
InChI: InChI=1S/C33H38N4O6/c1-3-22-23-16-21(43-32(40)36-14-10-20(11-15-36)35-12-6-5-7-13-35)8-9-27(23)34-29-24(22)18-37-28(29)17-26-25(30(37)38)19-42-31(39)33(26,41)4-2/h8-9,16-17,20,41H,3-7,10-15,18-19H2,1-2H3/t33-/m0/s1
InChIKey: UWKQSNNFCGGAFS-XIFFEERXSA-N

Uses

Its main use is in colon cancer, particularly in combination with other chemotherapy agents. This includes the regimen FOLFIRI which consists of infusional 5-fluorouracil, leucovorin, and irinotecan.

Safety Profile

Hazard Codes: Harmful Xn
Risk Statements: 22
R22:Harmful if swallowed.
RTECS: DW1061000

Specification

Irinotecan , its cas register number is 97682-44-5. It also can be called (+)-Irinotecan ; Camptosar ; HSDB 7607 ;
Irinotecan ; Irinotecanum ; Irinotecanum [INN-Latin] ; UNII-7673326042 .The most significant adverse effects of irinotecan (CAS NO.97682-44-5) are severe diarrhea and extreme suppression of the immune system.