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Basic information

  • Name:

  • 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,(6R,7R)-

  • Superlist Name:
  • Latamoxef
  • CAS No.:

  • 64952-97-2

  • Formula:
  • C20H20 N6 O9 S
  • Synonyms:
  • 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-carboxy(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,(6R,7R)- (9CI);5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[carboxy(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,[6R-[6a,7a,7(R*)]]-;Lamoxactam;Latamoxef;Moxalactam;Moxam;Oxa-cephem;

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China (Mainland)(6)
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Chemistry

IUPAC Name: (6R,7R)-7-[[3-hydroxy-2-(4-hydroxyphenyl)-3-oxopropanoyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-
8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Synonyms: (6R,7R)-7-{[Carboxy(4-hydroxyphenyl)acetyl]amino}-7-(methyloxy)-3-{[(1-methyl-1H-tetrazol-5-yl)thio]methyl}-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ; (6R,7R)-7-{[Carboxy(4-hydroxyphenyl)acetyl]amino}-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ; 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, (6R,7R)- ; 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[carboxy(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, (6R,7R)- ; 7b-[2-Carboxy-2-(4-hydroxyphenyl)acetamido]-7a-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-1-oxa-1-dethia-3-cephem-4-carboxylic Acid  ; N-[(6R,7R)-2-Carboxy-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-en-7-yl]-2-(p-hydroxyphenyl)malonamic Acid
Molecular Structure of Latamoxef (CAS NO.64952-97-2) :
Molecular Formula of Latamoxef (CAS NO.64952-97-2) : C20H20N6O9S
Molecular Weight of Latamoxef (CAS NO.64952-97-2) : 520.47
CAS NO: 64952-97-2
EINECS : 265-287-9
Index of Refraction: 1.768
Surface Tension: 82.6 dyne/cm
Density: 1.77 g/cm3
Storage temp: 2-8°C

Uses

  Latamoxef (CAS NO.64952-97-2) has a good antibacterial effect a variety of Gram-negative bacteria.

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
women TDLo intravenous 480mg/kg/4D-I (480mg/kg) BLOOD: HEMORRHAGE Annals of Internal Medicine. Vol. 99, Pg. 126, 1983.

Safety Profile

WGK Germany 3
RTECS RN6824500

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