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Megestrol

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Name

Megestrol

EINECS 222-628-6
CAS No. 3562-63-8 Density 1.15 g/cm3
PSA 54.37000 LogP 4.00450
Solubility N/A Melting Point 207-208 °C(Solv: ethyl ether (60-29-7); acetone (67-64-1))
Formula C22H30O3 Boiling Point 500.4 °C at 760 mmHg
Molecular Weight 342.478 Flash Point 270.5 °C
Transport Information N/A Appearance white solid
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 3562-63-8 (Megestrol) Hazard Symbols N/A
Synonyms

17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione;

Article Data 8

Megestrol Chemical Properties

IUPAC Name: Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl-
The MF of Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl- (3562-63-8) is C22H30O3.

                                     
The MW of Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl- (3562-63-8) is 342.47.
Synonyms of Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl- (3562-63-8): Megestrol ; Megestrolo ; Megestrolum ; Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl- ; 17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione
Index of Refraction: 1.569 
Density: 1.15 g/ml
Flash Point: 270.5 °C 
Boiling Point: 500.4 °C 
EINECS: 222-628-6

Megestrol Uses

  Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl- (3562-63-8) is used for treat dysmenorrhea, dysfunctional uterine bleeding, endometriosis and endometrial adenocarcinoma.

Megestrol Specification

Megestrol is a progesterone derivative with antineoplastic properties used in the treatment of advanced carcinoma of the breast and endometrium. When given in relatively high doses, Megestrol can substantially increase appetite in most individuals, even those with advanced cancer.
Megestrol Acetate Oral Suspension (a form of Megestrol) is used primarily as an appetite enhancer. The method of appetite enhancement is not known, but it can cause high blood sugar.
Currently, it is manufactured under the trade name Megace
 

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