Welcome to LookChem.com Sign In|Join Free

Product Name

  • or
Home > Products > 

Midazolam maleate salt

This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.
  • Name Midazolam maleate salt
  • EINECS261-775-0
  • CAS No. 59467-94-6
  • DensityN/A
  • PSA104.78000
  • LogP3.47160
  • SolubilityN/A
  • Melting Point114-117° (solvated)
  • FormulaC18H13ClFN3.C4H4O4
  • Boiling Point496.9 °C at 760 mmHg
  • Molecular Weight441.846
  • Flash Point254.3 °C
  • Transport Information3249
  • AppearanceN/A
  • Safety36
  • Risk Codes22
  • Molecular Structure
    Molecular Structure of 59467-94-6 (Midazolam maleate salt)
  • Hazard SymbolsHarmfulXn
  • SynonymsHarmfulXn
  • Article Data4

Midazolam maleate salt Specification

The CAS register number of Midazolam maleate salt is 59467-94-6. It also can be called as 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine maleate and the IUPAC name about this chemical is (Z)-but-2-enedioic acid; 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine. Classification Code about this chemical are Anesthetic [intravenous] and Drug / Therapeutic Agent. This chemical is harmful if swallowed. When you are using it, wear suitable protective clothing.

Physical properties about Midazolam maleate salt are: (1)ACD/LogP: 3.93; (2)#H bond acceptors: 3 ; (3)#Freely Rotating Bonds: 1; (4)Polar Surface Area: 30.18Å2; (5)Flash Point: 254.3 °C; (6)Enthalpy of Vaporization: 76.47 kJ/mol; (7)Boiling Point: 496.9 °C at 760 mmHg; (8)Vapour Pressure: 5.21E-10 mmHg at 25°C.

Midazolam maleate salt is a short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C(O)\C=C/C(=O)O.Fc4ccccc4C/1=N/Cc3cnc(n3c2c\1cc(Cl)cc2)C
(2)InChI: InChI=1/C18H13ClFN3.C4H4O4/c1-11-21-9-13-10-22-18(14-4-2-3-5-16(14)20)15-8-12(19)6-7-17(15)23(11)13;5-3(6)1-2-4(7)8/h2-9H,10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
(3)InChIKey: XYGVIBXOJOOCFR-BTJKTKAUBD
(4)Std. InChI: InChI=1S/C18H13ClFN3.C4H4O4/c1-11-21-9-13-10-22-18(14-4-2-3-5-16(14)20)15-8-12(19)6-7-17(15)23(11)13;5-3(6)1-2-4(7)8/h2-9H,10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
(5)Std. InChIKey: XYGVIBXOJOOCFR-BTJKTKAUSA-N

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 86mg/kg (86mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 2180, 1981.
mouse LD50 oral 760mg/kg (760mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 2180, 1981.
 

Related Products

Hot Products

Post a RFQ