Product Name: Polymyxin (CAS NO.1406-11-7)

Molecular Formula: C₄₈H₈₂N₁₆O₁₄
Molecular Weight: 1107.2635g/mol
Mol File: 1406-11-7.mol
Density: 1.36 g/cm³
Surface Tension: 76.4 dyne/cm
XLogP3-AA: -8
H-Bond Donor: 19
H-Bond Acceptor: 19
Structure Descriptors of Polymyxin (CAS NO.1406-11-7):
  InChI : InChI=1/C48H82N16O14/c1-24(2)22-34-44(73)57-28(10-16-49)38(67)56-31(13-19-52)42(71)63-36(25(3)65)46(75)54-21-15-33(41(70)55-29(11-17-50)40(69)61-35(45(74)60-34)23-27-8-6-5-7-9-27)58-39(68)30(12-18-51)59-47(76)37(26(4)66)64-43(72)32(14-20-53)62-48(77)78/h5-9,24-26,28-37,62,65-66H,10-23,49-53H2,1-4H3,(H,54,75)(H,55,70)(H,56,67)(H,57,73)(H,58,68)(H,59,76)(H,60,74)(H,61,69)(H,63,71)(H,64,72)(H,77,78)/t25-,26-,28+,29+,30+,31+,32+,33+,34+,35-,36+,37+/m1/s1    
  Smiles: CC(C)C[C@@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CCN)NC(=O)[C@H](CCNC(=O)[C@@H](NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC1=O)[C@@H](C)O)NC(=O)[C@H](CCN)NC(=O)[C@@H](NC(=O)[C@H](CCN)NC(O)=O)[C@@H](C)O

Polymyxin antibiotics are considered relatively neurotoxic and nephrotoxic[6] and, though effective, are therefore used only if less toxic antibiotics are ineffective or are contraindicated. Typical use cases are infections with strains of Pseudomonas aeruginosa or Enterobacteriaceae species that are highly resistant to other types of antibiotics such as cephalosporins.
Polymyxins (CAS NO.1406-11-7) are used to neutralize or absorb LPS contaminating samples that are intended for use in e.g. immunological experiments. Minimization of LPS contamination can be important because LPS can evoke strong reactions from immune cells and therefore distort experimental results.

Poison by intraperitoneal, subcutaneous, and intravenous routes. An additive permitted in food for human consumption.

 Polymyxin ,its CAS NO. is 1406-11-7,the synonyms is B-71 ; Caswell No. 678 ; EPA Pesticide Chemical Code 006305 ; Polymyxinum .