Phenol, 4-methyl-2-(1-propenyl)-

Base Information

• Chemical Name: Phenol, 4-methyl-2-(1-propenyl)-
• CAS No.: 53889-94-4
• Molecular Formula: C10H12O
• Molecular Weight: 148.205
• Mol file: 53889-94-4.mol

Synonyms:4-methyl-2-(1-propenyl)-phenol;2-Propenyl-4-methylphenol;Phenol,4-methyl-2-(1-propenyl);4-Oxy-1-methyl-3-propenyl-benzol;4-Methyl-2-propenyl-phenol;4-methyl-2-(prop-1-enyl)phenol;Phenol, 4-methyl-2-(1-propenyl)-;

Chemical Property of Phenol, 4-methyl-2-(1-propenyl)-

Chemical Property:

• Refractive Index: 1.5727 (estimate)
• Boiling Point: 228.81°C (rough estimate)
• PSA: 20.23000
• Density: 1.0170
• LogP: 2.73370

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Phenol, 4-methyl-2-(1-propenyl)-

There total 6 articles about Phenol, 4-methyl-2-(1-propenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-allyl-4-methylphenol (6628-06-4) → 4-methyl-2-(prop-1-enyl)phenol (53889-94-4)

Guidance literature:

With potassium hydroxide; In methanol; at 150 ℃; for 3h; Microwave irradiation;

DOI:10.1016/j.foodchem.2015.09.007

Reference yield:

phenol (108-95-2,27073-41-2) → o-Hydroxyethylbenzene (90-00-6) + 3-ethylphenol (620-17-7) + carvacrol (499-75-2) + 2,6-diisopropylphenol (2078-54-8) + 2,3-Dimethylphenol (526-75-0) + 4-methyl-2-(prop-1-enyl)phenol (53889-94-4) + 2,5-diethyl phenol (876-20-0) + 2-(methylallyl)phenol (20944-88-1)

Guidance literature:

With molybdenum(VI) oxide; In ethanol; at 280 ℃; for 4h; Inert atmosphere;

Reference yield:

2-hydroxy-5-methylbenzaldehyde (613-84-3) + ethyltriphenylphosphonium bromide (1530-32-1) → 4-methyl-2-(prop-1-enyl)phenol (53889-94-4)

Guidance literature:

ethyltriphenylphosphonium bromide; With potassium tert-butylate; In tetrahydrofuran; toluene; for 4h;

2-hydroxy-5-methylbenzaldehyde; In tetrahydrofuran; toluene; at -78 - 20 ℃; for 12h; Further stages.;

DOI:10.1021/ja070263u

upstream raw materials:

2-allyl-4-methylphenol

2-hydroxy-5-methylbenzaldehyde

ethyltriphenylphosphonium bromide

allyl p-tolyl ether

Downstream raw materials:

2-propyl-4-methylphenol

4-methyl-2-(5-methyl-[1,3]dioxan-4-yl)-phenol

C₁₅H₂₁NO₂

Refernces

• 1、 Marteau, Clémentine,Guitard, Romain,Penverne, Christophe,Favier, Dominique,Nardello-Rataj, Véronique,Aubry, Jean-Marie. "Boosting effect of ortho-propenyl substituent on the antioxidant activity of natural phenols". supporting information. p. 418 - 427. Retrieved 2015/10/19.