Glucaric acid

Base Information

• Chemical Name: Glucaric acid
• CAS No.: 87-73-0
• Deprecated CAS: 57030-41-8,910024-64-5
• Molecular Formula: C6H10O8
• Molecular Weight: 210.141
• Hs Code.: 2918199090
• European Community (EC) Number: 201-768-1
• UNII: QLZ991V4A2
• DSSTox Substance ID: DTXSID60859455,DTXSID501340165
• Nikkaji Number: J9.318A
• Wikipedia: Saccharic_acid
• Wikidata: Q424636
• Metabolomics Workbench ID: 2024
• ChEMBL ID: CHEMBL1794737
• Mol file: 87-73-0.mol

Synonyms:Acid, Saccharic;Anhydrous Calcium Glucarate;Anhydrous Calcium Saccharate;Calcium Glucarate;Calcium Glucarate, Anhydrous;Calcium Saccharate;Calcium Saccharate Anhydrous;Calcium Saccharate Tetrahydrate;Calcium Saccharate, Anhydrous;D Glucaric Acid;D Saccharic Acid;D-Glucaric Acid;D-Saccharic Acid;Glucarate, Anhydrous Calcium;Glucarate, Calcium;Glucaric Acid;Glucosaccharic Acid;L Gularic Acid;L-Gularic Acid;Levo Gularic Acid;Levo-Gularic Acid;Saccharate Tetrahydrate, Calcium;Saccharate, Anhydrous Calcium;Saccharate, Calcium;Saccharic Acid;Tetrahydrate, Calcium Saccharate;Tetrahydroxyadipic Acid

Chemical Property of Glucaric acid

Chemical Property:

• Vapor Pressure: 4.04E-27mmHg at 25°C
• Melting Point: 125-126°
• Refractive Index: 1.638
• Boiling Point: 766.4 °C at 760 mmHg
• PKA: 2.99±0.35(Predicted)
• Flash Point: 431.2 °C
• PSA: 155.52000
• Density: 1.939 g/cm³
• LogP: -3.40080
• Storage Temp.: Store at RT.
• XLogP3: -2.5
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 5
• Exact Mass: 210.03756727
• Heavy Atom Count: 14
• Complexity: 202

Purity/Quality:

98%, ^*data from raw suppliers

D-GLUCARIC ACID 85.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(C(C(=O)O)O)O)(C(C(=O)O)O)O
• Isomeric SMILES: [C@H]([C@@H]([C@@H](C(=O)O)O)O)([C@H](C(=O)O)O)O
• Description: Saccharic acid, also called glucaric acid, is a chemical compound with the formulaC6H10O8. It is derived by oxidizing a sugar such as glucose with nitric acid. The salts of saccharic acid are called saccharates.

Technology Process of Glucaric acid

There total 93 articles about Glucaric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.1%

D-glucaric acid monopotassium salt (576-42-1) → D-glucaric acid (87-73-0,7231-46-1) + D-Glucaro-1,4-lacton (389-36-6,13374-41-9,18404-60-9) + D-glucaro-6,3-lactone (2782-04-9,13374-41-9,18404-60-9)

Guidance literature:

With H⁽¹⁺⁾ resin Rexyn 100(H); In water; for 3h;

DOI:10.1021/jo960201e

Reference yield: 35.0%

D-glucose (50-99-7) → formic acid (64-18-6) + gluconic acid (526-95-4) + D-glucaric acid (87-73-0,7231-46-1)

Guidance literature:

With dihydrogen peroxide; 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate; In water; at 60 ℃; for 18h;

DOI:10.1016/j.cattod.2016.06.040

Reference yield: 31.0%

D-glucose (50-99-7) → gluconic acid (526-95-4) + D-glucaric acid (87-73-0,7231-46-1)

Guidance literature:

With oxygen; sodium hydroxide; In water; at 60 ℃; for 24h; under 7500.75 Torr; Temperature; Pressure; Reagent/catalyst; Catalytic behavior; Autoclave;

DOI:10.1002/cctc.201700089

upstream raw materials:

D-glucose

glucose

gluconic acid

gluconic acid

Downstream raw materials:

L-Tartaric acid

idaric acid bis-(N'-phenyl-hydrazide)

3-hydroxy-2-pyrone

2-furanoic acid

Refernces

• 1、 Zhang, Quanquan,Ge, Yanchun,Yang, Changjun,Zhang, Bingguang,Deng, Kejian. "Enhanced photocatalytic performance for oxidation of glucose to value-added organic acids in water using iron thioporphyrazine modified SnO2". supporting information. p. 5019 - 5029. Retrieved 2019/09/30.
• 2、 Chen, Rui,Yang, Changjun,Zhang, Quanquan,Zhang, Bingguang,Deng, Kejian. "Visible-light-driven selective oxidation of glucose in water with H-ZSM-5 zeolite supported biomimetic photocatalyst". . p. 297 - 305. Retrieved 2019/05/24.