Benzenesulfonic acid, 4-methyl-, 2-(aminocarbonyl)hydrazide

Base Information

• Chemical Name: Benzenesulfonic acid, 4-methyl-, 2-(aminocarbonyl)hydrazide
• CAS No.: 10396-10-8
• Molecular Formula: C8H11N3O3S
• Molecular Weight: 229.26
• Hs Code.: 2935009090
• European Community (EC) Number: 233-857-6
• DSSTox Substance ID: DTXSID0065062
• Nikkaji Number: J70.204H
• Wikidata: Q72509270
• Mol file: 10396-10-8.mol

Synonyms:4-toluenesulfonyl semicarbazide;p-toluenesulfonyl semicarbazide

Chemical Property of Benzenesulfonic acid, 4-methyl-, 2-(aminocarbonyl)hydrazide

Chemical Property:

• Appearance/Colour: white powder
• Melting Point: 236 °C
• Refractive Index: 1.588
• PKA: 8.92±0.43(Predicted)
• PSA: 109.67000
• Density: 1.381 g/cm³
• LogP: 2.41950
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C
• XLogP3: 0.2
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 229.05211239
• Heavy Atom Count: 15
• Complexity: 315

Purity/Quality:

99.9% ^*data from raw suppliers

p-Toluenesulfonylsemicarbazide 90.0 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)NNC(=O)N
• Uses: Blowing Agent RA is high temperature foaming agent, so it's especially suitable for high temperature processing plastic. As a foaming agent, it can be used to produce synthetic rubber,for example:Hard PVC, High density polyethylene, polypropylene, polycarbonate, nylon, ABS, natural rubber, SBR,etc. The processing of this product is safe,and without the risk of foam in advance. Adding some active agent, it's suitable for low temperature foaming agent, for example: after using urea of surface treatment,it can reduce decomposition temperature. p-toluenesulfonyl semicarbazide is high-temperature N2 blowing agent .It can particularly used in high-temperature processing plastic such as ABS resin ,nylon,hard PVC ,HIDE,polypropylene,polycarbonate etc.

Technology Process of Benzenesulfonic acid, 4-methyl-, 2-(aminocarbonyl)hydrazide

There total 4 articles about Benzenesulfonic acid, 4-methyl-, 2-(aminocarbonyl)hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

hydrazine carboxamide (4426-72-6,51433-48-8,57-56-7) + p-toluenesulfonyl chloride (98-59-9) → N4-(4-Toluenesulfonyl)semicarbazide (10396-10-8)

Guidance literature:

aluminum oxide; for 0.25h;

DOI:10.1002/jccs.200700220

Reference yield:

C9H9Cl3N2O4S → N4-(4-Toluenesulfonyl)semicarbazide (10396-10-8)

Guidance literature:

With ammonium chloride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃; for 0.166667h;

DOI:10.1515/znb-2007-0516

Reference yield:

Azodicarboxamid (123-77-3,97707-96-5) + sodium 4-methylbenzenesulfinate (824-79-3) → N4-(4-Toluenesulfonyl)semicarbazide (10396-10-8)

Guidance literature:

In dimethyl sulfoxide;

DOI:10.1021/jo00863a026

upstream raw materials:

Azodicarboxamid

sodium 4-methylbenzenesulfinate

hydrazine carboxamide

p-toluenesulfonyl chloride

Downstream raw materials:

C₁₁H₁₅N₃O₅S

N,N,N'-Tris-(2-cyan-aethyl)-N'-p-toluolsulfonylhydrazin

1-p-Toluenesulfonyl-1-Carbisopropoxy-2-Carbamyl Hydrazine

C₁₃H₁₉N₃O₅S

Refernces

• 1、 Safaei-Ghomi, Javad,Bamoniri, Abdolhamid,Abbaszadeh-Nooshabady, Aboalfazl. "A convenient procedure for the preparation of sulfonamidoureas using triphosgene". . p. 721 - 724. Retrieved 2008/10/09.