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Sodium lauryl sulfate

  • Name Sodium lauryl sulfate
  • EINECS205-788-1
  • CAS No. 151-21-3
  • Density1.03 g/mL at 20 °C
  • PSA74.81000
  • LogP4.46490
  • Solubilitywater: 0.1 M, clear to nearly clear, colorless to slightly yellow
  • Melting Point204-207 °C(lit.)
  • FormulaC12H25NaO4S
  • Boiling PointN/A
  • Molecular Weight288.384
  • Flash Point>100 °C
  • Transport InformationUN 2926 4.1/PG 2
  • AppearanceClear to yellow liquid
  • Safety26-36/37-36/37/39-36-22
  • Risk Codes36/37/38-36/38-22-11-21/22-42-41-20/21/22
  • Molecular Structure
    Molecular Structure of 151-21-3 (Sodium dodecyl sulfate)
  • Hazard SymbolsIrritantXi,HarmfulXn,FlammableF
  • SynonymsIrritantXi,HarmfulXn,FlammableF
  • Article Data20

Sodium lauryl sulfate Specification

Sodium lauryl sulfate, its CAS NO. is 151-21-3, the synonyms are Sulfuric acid monododecyl ester sodium salt ; Dodecyl sulfate, sodium salt . Sodium dodecyl sulfate is an organic compound with the formula CH3(CH2)11OSO3Na. It is an anionic surfactant used in many cleaning and hygiene products.

Preparation of Sodium lauryl sulfate: Sodium dodecyl sulfate is synthesized by treating lauryl alcohol with sulfur trioxide gas, oleum, or chlorosulfuric acid to produce hydrogen lauryl sulfate.

Uses of Sodium lauryl sulfate: Sodium lauryl sulfate is a highly effective surfactant used in any task requiring the removal of oily stains and residues. It is used in lower concentrations with toothpastes, shampoos, shaving foams, some dissolvable aspirins, enemas, and fiber therapy caplets. Sodium lauryl sulfate can also be used to aid in lysing cells during DNA extraction and for unraveling proteins in SDS-PAGE.

When you are using Sodium lauryl sulfate, please be cautious about it as the following:
1. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice;
2. Wear suitable protective clothing and gloves;
3. Wear suitable protective clothing, gloves and eye/face protection;
4. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice;

You can still convert the following datas into molecular structure:
(1)InChI=1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1;
(2)InChIKey=DBMJMQXJHONAFJ-UHFFFAOYSA-M;
(3)SmilesC(CCCCCCCCCC)COS(=O)(=O)[O-].[Na+];

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 250mg/kg (250mg/kg) VASCULAR: REGIONAL OR GENERAL ARTERIOLAR OR VENOUS DILATION

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 42, Pg. 283, 1953.
mouse LD50 intravenous 118mg/kg (118mg/kg)   Journal of Pharmaceutical Sciences. Vol. 52, Pg. 803, 1963.
 
rabbit LDLo skin 10gm/kg (10000mg/kg) GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

BEHAVIORAL: ATAXIA
BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 23-3/1971,
rat LC50 inhalation > 3900mg/m3/1H (3900mg/m3)   BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 23-3/1971,
rat LD50 intraperitoneal 210mg/kg (210mg/kg)   Proceedings of the Scientific Section of the Toilet Goods Association. Vol. 3, Pg. 1, 1945.
rat LD50 intravenous 118mg/kg (118mg/kg)   Journal of Pharmaceutical Sciences. Vol. 52, Pg. 803, 1963.
 
rat LD50 oral 1288mg/kg (1288mg/kg)   Food and Cosmetics Toxicology. Vol. 5, Pg. 763, 1967.
 

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